CD79B

Gene Symbol CD79B
Entrez Gene 974
Alt Symbol AGM6, B29, IGB
Species Human
Gene Type protein-coding
Description CD79b molecule, immunoglobulin-associated beta
Other Description B-cell antigen receptor complex-associated protein beta chain|B-cell-specific glycoprotein B29|CD79b antigen (immunoglobulin-associated beta)|Ig-beta|immunoglobulin-associated B29 protein
Swissprots P40259 Q53FS2 Q9BU06
Accessions AAA72424 AAA98831 CCF76965 CCF76966 CCF76967 CDM22282 EAW94227 EAW94228 EAW94229 EAW94230 EAW94231 EAW94232 P40259 AK222954 BAD96674 AK223210 BAD96930 AK313583 BAG36353 AX775815 CAE11607 AX775817 CAE11608 BC002975 AAH02975 BC030210 AAH30210 BC032651 AAH32651 M80461 AAA58387 M89957 AAA64459 S52229 AAB24822 S79249 AAC60654 X83539 CAA58522 XM_005257858 XP_005257915 NM_000626 NP_000617 NM_001039933 NP_001035022 NM_021602 NP_067613
Function Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. {ECO:0000269|PubMed:12097390, ECO:0000269|PubMed:8617796, ECO:0000269|PubMed:9057631}.
Subcellular Location Cell membrane; Single-pass type I membrane protein. Note=Following antigen binding, the BCR has been shown to translocate from detergent-soluble regions of the cell membrane to lipid rafts although signal transduction through the complex can also occur outside lipid rafts. {ECO:0000250}.
Tissue Specificity B-cells.
Top Pathways B cell receptor signaling pathway

CD79B (B-4) - sc-373808 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD79B (B-4): sc-373808. Western blot analysis of CD79B expression in Ramos (A), Raji (B), NAMALWA (C) and HL-60 (D) whole cell lysates.

CD79B (G-7) - sc-166675 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD79B (G-7): sc-166675. Western blot analysis of CD79B expression in Raji whole cell lysate.

CD79B (H-3) - sc-373843 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD79B (H-3): sc-373843. Western blot analysis of CD79B expression in non-transfected: sc-117752 (A) and human CD79B transfected: sc-115257 (B) 293T whole cell lysates.

CD79B (AT105-1) - sc-59114 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD79B (AT105-1): sc-59114. Western blot analysis of CD79B expression in Ramos (A) and Raji (B) whole cell lysates.

CD79B (C-19) - sc-8505 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CD79B (C-19): sc-8505. Western blot analysis of CD79B expression in Ramos (A), Raji (B) and Daudi (C) whole cell lysates.

CD79B (N-20) - sc-8504 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CD79B (N-20): sc-8504. Western blot analysis of CD79B expression in Ramos (A), NAMALWA (B) and Raji (C) whole cell lysates.

CD79B (SN8/3A2-2E7) - sc-80538 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD79B (SN8/3A2-2E7): sc-80538. Western blot analysis of CD79B expression in non-transfected 293T: sc-117752 (A), human CD79B transfected 293T: sc-115257 (B) and Raji (C) whole cell lysates.

CD79B (ZL9-3) - sc-13530 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD79B (ZL9-3) FITC: sc-13530 FITC. FCM analysis of GA-10 cells. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>: sc-2855.

CD79B (SN8) - sc-18902 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD79B (SN8) FITC: sc-18902 FITC. FCM analysis of GA-10 cells. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>: sc-2855.

CD79B (FL-229) - sc-25605 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CD79B (FL-229): sc-25605. Immunoperoxidase staining of formalin fixed, paraffin-embedded human malignant lymphoma tissue showing membrane staining of tumor cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

CD79B (AT107-2) - sc-59115 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal
CD79B (AT107-2): sc-59115. Western blot analysis of CD79B expression in Ramos (A) and Daudi (B) whole cell lysates.

CD79B (B29/123) - sc-53210 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD79B (B29/123): sc-53210. Immunoperoxidase staining of formalin fixed, paraffin-embedded human spleen tissue showing cytoplasmic staining of cells in white pulp and cells in red pulp.

Anti-CD79b antibody - ab175399 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence analysis of MCF7 cells using ab175399. Blue DAPI for nuclear staining.

Anti-CD79b antibody - ab167547 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CD79b antibody (ab167547) at 1 µg/mlLane 1 : CD79b transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysate

Anti-CD79b antibody - ab167491 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-CD79b antibody (ab167491) at 1 µg/mlLane 1 : CD79b transfected 293T cell lysate Lane 2 : Non-transfected 293T cell lysate Lysates/proteins at 15 µl per lane.SecondaryGoat anti-Mouse IgG HRP at 1/2500 dilution

Anti-CD79b antibody [AT105-1] - ab33293 from Abcam

Prices $379.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone AT105-1
Profile of staining of human peripheral blood lymphocytes with mouse anti-human CD79 beta antibody (ab33293).

Anti-CD79b antibody [AT105-1] (Phycoerythrin) - ab33295 from Abcam

Prices $185.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone AT105-1

Anti-CD79b antibody [AT107-2] - ab23826 from Abcam

Prices $372.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone AT107-2

Anti-CD79b antibody [AT107-2] (FITC) - ab33296 from Abcam

Prices $378.00
Sizes 50 µg
Host Rat
Clonality Monoclonal
Clone AT107-2
Staining of rat peripheral blood lymphocytes with ab33296 after permeabilisation.

Anti-CD79b antibody [CB3-1] - ab130422 from Abcam

Prices $373.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone CB3-1

Anti-CD79b antibody [CB3-1] - ab25632 from Abcam

Prices $372.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone CB3-1

Anti-CD79b antibody [CB3-1] (Allophycocyanin) - ab25169 from Abcam

Prices $373.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone CB3-1

Anti-CD79b antibody [CB3-1] (Biotin) - ab25615 from Abcam

Prices $372.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone CB3-1

Anti-CD79b antibody [CB3-1] (FITC) - ab25626 from Abcam

Prices $189.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone CB3-1
Overlay histogram showing RAMOS cells stained with ab25626 (red line). The cells were fixed with 4% paraformaldehyde (10 min) and incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab25626, 2µg/1x106 cells) for 30 min at 22ºC. Isotype control antibody (black line) was mouse IgG1 FITC (2µg/1x106 cells) used under the same conditions. Acquisition of >5,000 events was performed.Please note that Abcam do not have any data for use of this antibody on non-fixed cells. We welcome any customer feedback.

Anti-CD79b antibody [CB3-1] (PE/Cy5®) - ab25623 from Abcam

Prices $372.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone CB3-1
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