| Gene Symbol |
AAMP
|
| Entrez Gene |
14
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
angio-associated, migratory cell protein
|
| Other Description |
angio-associated migratory cell protein
|
| Swissprots |
Q8WUJ9 Q13685 Q96H92
|
| Accessions |
EAW70599 EAW70600 EAW70601 Q13685 AB209790 BAD93027 AK131047 AK225078 BC008809 AAH08809 BC014122 BC020244 AAH20244 BC039866 AAH39866 BG534787 CN277005 CR456755 CAG33036 DA277259 DA465288 HY374777 M95627 AAA68889 NM_001087 NP_001078 NM_001302545 NP_001289474
|
| Function |
Plays a role in angiogenesis and cell migration. In smooth muscle cell migration, may act through the RhoA pathway. {ECO:0000269|PubMed:10329261, ECO:0000269|PubMed:18634987}.
|
| Subcellular Location |
Cell membrane. Cytoplasm.
|
| Tissue Specificity |
Expressed in metastatic melanoma, liver, skin, kidney, heart, lung, lymph node, skeletal muscle and brain, and also in A2058 melanoma cells and activated T-cells (at protein level). Expressed in blood vessels. Strongly expressed in endothelial cells, cytotrophoblasts, and poorly differentiated. colon adenocarcinoma cells found in lymphatics. {ECO:0000269|PubMed:10329261, ECO:0000269|PubMed:7743515}.
|
![Western Blot: AAMP Overexpression Lysate (Adult Normal) [NBP2-08441] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for AAMP.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/14746_AAMP%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBP2-08441-img0001.jpg)