| Gene Symbol |
wdr1-a
|
| Entrez Gene |
398123
|
| Alt Symbol |
aip1, wdr1b
|
| Species |
Xenopus
|
| Gene Type |
protein-coding
|
| Description |
WD repeat domain 1
|
| Other Description |
WD repeat domain 1 b|WD repeat-containing protein 1-A|actin interacting protein 1|actin-interacting protein 1-A|xAIP1-A
|
| Swissprots |
Q6DEC6 Q9W7F2
|
| Accessions |
Q9W7F2 AF124140 AAD22062 BC041232 AAH41232 BC077202 AAH77202 NM_001088454 NP_001081923
|
| Function |
Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins. Doesn't sever actin filaments alone, but caps the barbed ends of filaments severed by cofilin, which blocks annealing and depolymerization and allows more extensive severing by cofilin. {ECO:0000269|PubMed:10212149, ECO:0000269|PubMed:12055192}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:10212149}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10212149}. Nucleus {ECO:0000269|PubMed:10212149}.
|