AKR1B10

Gene Symbol AKR1B10
Entrez Gene 57016
Alt Symbol AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI
Species Human
Gene Type protein-coding
Description aldo-keto reductase family 1, member B10 (aldose reductase)
Other Description ARP|SI reductase|aldo-keto reductase family 1 member B10|aldo-keto reductase family 1, member B11 (aldose reductase-like)|aldose reductase-like 1|aldose reductase-like peptide|aldose reductase-related protein|hARP|small intestine reductase
Swissprots O60218 A4D1P1 O75890 Q8IWZ1 Q6FHF3
Accessions EAL24069 EAW83816 O60218 AF044961 AAC15671 AF052577 AAC36465 AF524864 AAO13380 BC008837 AAH08837 BM975664 BT006794 AAP35440 CR541801 CAG46600 DQ890678 ABM81604 EU176471 ABW03272 U37100 AAC17469 XM_011516416 XP_011514718 XM_011516417 XP_011514719 XR_927491 NM_020299 NP_064695
Function Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs. {ECO:0000269|PubMed:18087047}.
Subcellular Location Lysosome {ECO:0000269|PubMed:21585341}. Secreted {ECO:0000269|PubMed:21585341}. Note=Secreted through a lysosome-mediated non-classical pathway.
Tissue Specificity Found in many tissues. Highly expressed in small intestine, colon and adrenal gland.
Top Pathways Pentose and glucuronate interconversions, Glycerolipid metabolism, Galactose metabolism, Fructose and mannose metabolism

AKR1B10 CRISPR/Cas9 KO Plasmid (h) - sc-403649 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AKR1B10 HDR Plasmid (h) - sc-403649-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AKR1B10 Double Nickase Plasmid (h) - sc-403649-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AKR1B10 Double Nickase Plasmid (h2) - sc-403649-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AKR1B10 CRISPR Activation Plasmid (h) - sc-403649-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AKR1B10 CRISPR Activation Plasmid (h2) - sc-403649-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AKR1B10 Lentiviral Activation Particles (h) - sc-403649-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AKR1B10 Lentiviral Activation Particles (h2) - sc-403649-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AKR1B10 siRNA (h) - sc-72341 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AKR1B10 shRNA Plasmid (h) - sc-72341-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AKR1B10 shRNA (h) Lentiviral Particles - sc-72341-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Aldo-keto Reductase 1B10/AKR1B10 RNAi - H00057016-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU106511 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3024 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3024 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02608 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02608

AKR1B10 siRNA (Human) - CRJ1288 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AKR1B10 - MBS8213537 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human AKR1B10 (NM_020299.4) - SHH234454 from Creative biogene

Category siRNA
Species Reactivities Human

Human AKR1B10 siRNA - orb271789 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AKR1B10 shRNA Plasmid (Human) - CHJ1288 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

AKR1B10 miRNA 3'UTR clone - MiUTR4H-TG00254 from Creative biogene

Species Reactivities Human
Search more