GRK1

Gene Symbol GRK1
Entrez Gene 6011
Alt Symbol GPRK1, RHOK, RK
Species Human
Gene Type protein-coding
Description G protein-coupled receptor kinase 1
Other Description rhodopsin kinase
Swissprots Q15835 Q53X14
Accessions AAC97160 AAC97161 AAQ94192 AAT00534 EAX09222 Q15835 AK289912 BAF82601 BC140945 AAI40946 BM702747 BX647503 L77503 AAG50439 U63973 AAB05929 NM_002929 NP_002920
Function Retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin (RHO), the G protein- coupled receptor that initiates the phototransduction cascade. This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination. {ECO:0000269|PubMed:15946941}.
Subcellular Location Membrane {ECO:0000250|UniProtKB:P28327}; Lipid-anchor {ECO:0000250|UniProtKB:P28327}.
Tissue Specificity Retinal-specific. Expressed in rods and cones cells. {ECO:0000269|PubMed:11717351}.
Top Pathways Endocytosis, Chemokine signaling pathway, Phototransduction

GRK 1 CRISPR/Cas9 KO Plasmid (h) - sc-406525 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GRK 1 HDR Plasmid (h) - sc-406525-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GRK 1 Double Nickase Plasmid (h) - sc-406525-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GRK 1 Double Nickase Plasmid (h2) - sc-406525-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GRK 1 CRISPR Activation Plasmid (h) - sc-406525-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GRK 1 CRISPR Activation Plasmid (h2) - sc-406525-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GRK 1 Lentiviral Activation Particles (h) - sc-406525-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GRK 1 Lentiviral Activation Particles (h2) - sc-406525-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GRK 1 siRNA (h) - sc-29336 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GRK 1 shRNA Plasmid (h) - sc-29336-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GRK 1 shRNA (h) Lentiviral Particles - sc-29336-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GRK 1 siRNA (h2) - sc-36208 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

GRK 1 shRNA Plasmid (h2) - sc-36208-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

GRK 1 shRNA (h2) Lentiviral Particles - sc-36208-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

GRK1 RNAi - H00006011-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® siRNA - SIHK0851 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK0853 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK0852 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN9696 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

GRK1 siRNA (Human) - CRH4078 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GRK1 - MBS8229567 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Grk1 (NM_002929.2) - SHH308030 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human GRK1(NM_002929.2) - SHH105293 from Creative biogene

Category siRNA
Species Reactivities Human

Human GRK1 siRNA - orb264580 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human
Search more