C1QA

Gene Symbol C1QA
Entrez Gene 712
Alt Symbol -
Species Human
Gene Type protein-coding
Description complement component 1, q subcomponent, A chain
Other Description complement C1q subcomponent subunit A|complement component 1, q subcomponent, alpha polypeptide|complement component C1q, A chain
Swissprots P02745 B2R4X2 Q5T963
Accessions AAV40828 EAW95014 EAW95015 P02745 AF135157 AAD32626 AF260332 AAG44663 AK311980 BAG34919 BC030153 AAH30153 BC071986 AAH71986 BG548439 BX369252 EU832816 ACE87827 GQ129447 ACT64581 HQ447673 ADQ32158 NM_015991 NP_057075
Function C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
Subcellular Location Secreted.
Top Pathways Complement and coagulation cascades, Systemic lupus erythematosus, Prion diseases, Chagas disease (American trypanosomiasis), Staphylococcus aureus infection

C1q-A (M-120) - sc-25856 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
C1q-A (M-120): sc-25856. Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic staining of cells in tubuli at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

C1q-A (H-40) - sc-25855 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
C1q-A (H-40): sc-25855. Western blot analysis of C1q-A expression in ECV304 whole cell lysate (A) and human spleen (B) and human kidney (C) tissue extracts.

C1q-A (C-14) - sc-27660 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
C1q-A (C-14): sc-27660. Immunoperoxidase staining of formalin fixed, paraffin-embedded human skin tissue showing cytoplasmic staining of keratinocytes, melanocytes, epidermal cells and Langerhans.

C1q-A (D-15) - sc-27659 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

C1q-A (V-20) - sc-27658 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-C1q antibody - ab14004 from Abcam

Prices $384.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal
ELISA standard curve.  ab14004 used as primary antibody (0.1µg/ml), human C1q used as test antigen and a goat anti IgY-HRP as a secondary antibody.

Anti-C1q antibody - ab8779 from Abcam

Prices $368.00
Sizes 1 ml
Host Sheep
Clonality Polyclonal

Anti-C1q antibody - ab182923 from Abcam

Host Goat
Clonality Polyclonal

Anti-C1q antibody [7H8] - ab11861 from Abcam

Prices $392.00
Sizes 50 µg
Host Rat
Clonality Monoclonal
Clone 7H8
ab11861 staining C1q (green) in human SHSY5Y cells by ICC/IF (Immunocytochemistry/immunofluorescence). Cells were fixed with 1% paraformaldehyde and blocked with 10% serum for 20 minutes at room temperature. Samples were incubated with primary antibody (1/50 in PBS) for 2 hours at 24°C. An undiluted Alexa Fluor®488-conjugated goat anti-rat IgG polyclonal was used as the secondary antibody. Counterstained with Hoechst 33258 (blue) for 10 minutes at room temperature.See Abreview

Anti-C1q antibody [9A7] - ab71089 from Abcam

Prices $388.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 9A7
All lanes : Anti-C1q antibody [9A7] (ab71089) at 1/1000 dilutionLane 1 : K562 cell lysateLane 2 : Jurkat T cell lysateLane 3 : C6 cell lysateLane 4 : NIH3T3 cell lysate

Anti-C1q antibody (Biotin) - ab48341 from Abcam

Prices $370.00
Sizes 150 µg
Host Rabbit
Clonality Polyclonal

Anti-C1q antibody (FITC) - ab4223 from Abcam

Prices $388.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal
ab4223, staining C1q in CHO-K1 cells transfected with M1-AQP4 or M23-AQP4 by Immunocytochemistry/ Immunofluorescence. Cells were incubated at room temperature with recombinant monoclonal NMO antibody and 120 µg/ml human C1q protein (ab96363). Cells were washed with PBS, fixed in paraformaldehyde and permeabilized with 0.1% Triton X-100. Cells were blocked with 1% BSA for 30 min and incubated for 60 min with primary antibody against C1q (ab4223) at 1/200 dilution.

Anti-C1q antibody (FITC) - ab182940 from Abcam

Host Goat
Clonality Polyclonal

Anti-C1q antibody (HRP) - ab46191 from Abcam

Prices $376.00
Sizes 1 ml
Host Sheep
Clonality Polyclonal

Anti-C1q antibody [JL-1] - ab71940 from Abcam

Prices $394.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone JL-1
ab71940 staining C1q in rat spleen tissue by Immunohistochemistry (Frozen sections).Tissue was fixed in paraformaldehyde, blocked with 10% serum for 30 minutes at 24°C then incubated with ab71940 at a 1/50 dilution for 16 hours at 4°C. The seconday used was an Alexa-Fluor 488 conjugated goat anti-mouse polyclonal used at a 1/1000 dilution.See Abreview

Anti-C1q antibody [JL-1] (Biotin) - ab72355 from Abcam

Prices $378.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone JL-1

Anti-C1q antibody, prediluted - ab30539 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-C1QA antibody - ab155052 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-C1QA antibody (ab155052) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

Anti-C1QA antibody - ab89687 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-C1QA antibody (ab89687) at 1 µg/ml + human kidney tissue lysate at 50 µg

Anti-C1QA antibody - ab191222 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-C1QA antibody (ab191222) at 1/1000 dilution + Human blood plasma tissue lysate at 35 µgSecondarygoat anti-rabbit IgG H&L(HRP) at 1/5000 dilution

Anti-C1QA antibody [EPR14634] - ab189922 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14634
All lanes : Anti-C1QA antibody [EPR14634] (ab189922) at 1/10000 dilutionLane 1 : Human plasma lysateLane 2 : Human serum lysateLane 3 : Human spleen lysateLysates/proteins at 20 µg per lane.SecondaryAnti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

Anti-C1QA antibody [EPR2979(2)] - ab108325 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR2979(2)
All lanes : Anti-C1QA antibody [EPR2979(2)] (ab108325) at 1/1000 dilutionLane 1 : Human plasma lysateLane 2 : Human serum lysates Lysates/proteins at 10 µg per lane.

Anti-C1QA antibody [EPR2980Y] - ab76425 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR2980Y
Anti-C1QA antibody [EPR2980Y] (ab76425) at 1/1000 dilution + human plasma lysate at 10 µgSecondarygoat anti-rabbit HRP at 1/1000 dilution

Anti-C1QA antibody - C-terminal - ab85208 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-C1QA antibody - C-terminal (ab85208) at 1/50 dilution + Jurkat cell line lysates at 35 µg

Anti-Complement C1QA Antibody (clone 7H8) - LS-C20977 from LifeSpan Bioscience

Host Rat
Clonality Monoclonal
Clone 7H8
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