| Gene Symbol |
ABHD12
|
| Entrez Gene |
26090
|
| Alt Symbol |
ABHD12A, BEM46L2, C20orf22, PHARC, dJ965G21.2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
abhydrolase domain containing 12
|
| Other Description |
2-arachidonoylglycerol hydrolase|abhydrolase domain-containing protein 12|monoacylglycerol lipase ABHD12
|
| Swissprots |
Q5T710 B4DE71 Q5T711 A6NED4 Q8N2K0 Q96CR1 Q9BX05 Q9NPX7 A6NJ90 Q9UFV6 A8K450
|
| Accessions |
EAX10088 EAX10089 EAX10090 Q8N2K0 AK075023 BAC11357 AK290815 BAF83504 AK293495 BAG56982 AL117442 CAB55927 BC014049 AAH14049 BQ574269 BQ672998 BQ961739 HQ448169 ADQ32650 XM_005260698 XP_005260755 XM_005260699 XP_005260756 XM_005260700 XP_005260757 XM_011529214 XP_011527516 XM_011529215 XP_011527517 XM_011529216 XP_011527518 XM_011529217 XP_011527519 XM_011529218 XP_011527520 NM_001042472 NP_001035937 NM_015600 NP_056415
|
| Function |
Lysophosphatidylserine (LPS) lipase that plays a key role in the central nervous system. Represents a major LPS lipase in the brain (By similarity). May also have a 2- arachidonoylglycerol (2-AG) hydrolase activity and act as a regulator of endocannabinoid signaling pathways. {ECO:0000250|UniProtKB:Q99LR1, ECO:0000269|PubMed:22969151, ECO:0000269|PubMed:24027063}.
|
| Subcellular Location |
Membrane {ECO:0000250|UniProtKB:Q99LR1}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q99LR1}.
|