CLN3

Gene Symbol CLN3
Entrez Gene 1201
Alt Symbol BTS, JNCL
Species Human
Gene Type protein-coding
Description ceroid-lipofuscinosis, neuronal 3
Other Description batten disease protein|battenin
Swissprots Q13286 B2R7J1 Q9UP12 O95089 Q9UP13 O00668 B4DXL3 Q9UP14 Q9UP09 Q549S9 Q9UP11
Accessions AAC05337 AAC27430 CAA68148 CAH05564 EAW52281 EAW52282 EAW52283 EAW52284 EAW52285 EAW52286 EAW52287 EAW52288 EAW52289 EAW52290 EAW52291 EAW52292 EAW52293 EAW52294 EAW52295 EAW52296 EAW52297 EAW52298 EAW52299 Q13286 AF015593 AAD01555 AF015594 AAD01556 AF015595 AAD01557 AF015596 AAD01558 AF015597 AAD01559 AF015598 AAD01560 AF015599 AAD01561 AF015600 AAD01562 AF015601 AAD01563 AF015602 AAD01564 AF077956 AAD51478 AF077957 AAD51479 AF077958 AAD51480 AF077959 AAD51481 AF077960 AAD51482 AF077961 AAD51483 AF077962 AAD51484 AF077963 AAD51485 AF077964 AAD51486 AF077965 AAD51487 AF077966 AAD51488 AF077967 AAD51489 AF077968 AAD51490 AF077969 AAD51491 AF077970 AAD51492 AF077971 AAD51493 AF077972 AAD51494 AF077973 AAD51495 AF078168 AAD48542 AF078169 AAD48543 AI138575 AK090709 AK294070 BAG57414 AK294250 BAG57546 AK295500 BAG58420 AK297690 BAG60048 AK302027 BAG63425 AK302138 BAG63512 AK313002 BAG35838 AU105965 BC002394 AAH02394 BC004433 AAH04433 BC111068 AAI11069 BK001540 DAA02067 BP252176 DA552461 DA703317 DA869025 DB101039 EF587244 ABW04812 EF587245 ABW04813 U32680 AAB51075 NM_000086 NP_000077 NM_001042432 NP_001035897 NM_001286104 NP_001273033 NM_001286105 NP_001273034 NM_001286109 NP_001273038 NM_001286110 NP_001273039
Function Involved in microtubule-dependent, anterograde transport of late endosomes and lysosomes. {ECO:0000269|PubMed:22261744}.
Subcellular Location Lysosome membrane {ECO:0000269|PubMed:17286803, ECO:0000269|PubMed:17897319}; Multi- pass membrane protein {ECO:0000269|PubMed:17286803, ECO:0000269|PubMed:17897319}. Late endosome {ECO:0000269|PubMed:17286803}.
Top Pathways Lysosome

CLN3 (C-1) - sc-398192 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CLN3 (C-1): sc-398192. Western blot analysis of CLN3 expression in HeLa (A) and Jurkat (B) whole cell lysates and human hippocampus (C) and mouse brain (D) tissue extracts.

CLN3 (D-20) - sc-49625 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CLN3 (D-20): sc-49625. Western blot analysis of CLN3 expression in non-transfected 293T: sc-117752 (A), mouse CLN3 transfected 293T: sc-126644 (B) and HeLa (C) whole cell lysates.

CLN3 (C-16) - sc-49624 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CLN3 (C-16): sc-49624. Western blot analysis of CLN3 expression in rat brain tissue extract.

CLN3 (E-19) - sc-49626 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CLN3 (N-19) - sc-49627 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CLN3 (N-19): sc-49627. Western blot analysis of CLN3 expression in HeLa whole cell lysate.

CLN3 (H-300) - sc-134452 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-CLN3 antibody - ab192473 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CLN3 antibody - ab202331 from Abcam

Prices $359.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CLN3 antibody (ab202331) at 1/1000 dilutionLane 1 : A431 cell lysateLane 2 : KG-1 cell lysateLane 3 : SH-SY5Y cell lysateLane 4 : Mouse kidney tissue lysateLane 5 : Mouse liver tissue lysateLysates/proteins at 20 µg per lane.SecondaryGoat anti-rabbit IgG H&L(HRP) at 1/10000 dilution

Anti-CLN3 antibody - ab54687 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab54687 CLN3 antibody at 1ug/ml.

Anti-CLN3 Antibody - LS-C341729 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CLN3 Antibody - LS-C309931 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CLN3 Antibody - LS-C331768 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of SH-SY5Y cell line, using CLN3 antibody.

Anti-CLN3 Antibody (clone 1G10) - LS-C196935 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1G10
Western Blot analysis of CLN3 expression in transfected 293T cell line by CLN3 monoclonal antibody (M03), clone 1G10.Lane 1: CLN3 transfected lysate(47.623 KDa).Lane 2: Non-transfected lysate.

Anti-CLN3 Antibody (aa250-284) - LS-C344442 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysates from A431, KG-1, SH-SY5Y cell line, mouse kidney, mouse liver tissue (from left to right) with CLN3 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20 ug per lane.

CLN3 Antibody - H00001201-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: CLN3 Antibody [H00001201-D01P] - Analysis of CLN3 expression in mouse kidney.

CLN3 Antibody (1G10) - H00001201-M03 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1G10
Western Blot: CLN3 Antibody (1G10) [H00001201-M03] - Analysis of CLN3 expression in transfected 293T cell line by CLN3 monoclonal antibody (M03), clone 1G10. Lane 1: CLN3 transfected lysatE (47.623 KDa). Lane 2: Non-transfected lysate.

CLN3 Polyclonal Antibody - bs-8016R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CLN3 antibody produced in rabbit - SAB1410211 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CLN3: <B>Cat. No. SAB1410211</B>: Antibody concentration: 1-5 μg/mL. Specific band of ~47.8 kDa using mouse kidney lysate.

ANTI-CLN3 (CENTER) antibody produced in rabbit - SAB1305007 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CLN3 (Center): <B>Cat. No. SAB1305007</B>: CLN3 Antibody (Center) western blot analysis in Jurkat cell line lysates (35 μg/lane).

Monoclonal Anti-CLN3 antibody produced in mouse - WH0001201M3 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1G10
<B>Immunoblotting</B><BR/>Monoclonal Anti-CLN3, <B>Cat. No. WH0001201M3</B> used at the antibody concentration: 1 μg/mL. Specific band of ~74.29 kDa using immunogen protein lysate.

CLN3-Antibody-Center - AP13304c from Abgent, a WuXi AppTec company

Host Rabbit
Clonality Polyclonal
CLN3 Antibody (Center) (Cat. #AP13304c) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the CLN3 antibody detected the CLN3 protein (arrow).

CLN3-Antibody-monoclonal-M03 - AT1561a from Abgent, a WuXi AppTec company

Prices $315.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1G10
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (73.92 KDa) .

CLN3-Antibody-Center - AP20845c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Flow cytometric analysis of Hela cells using CLN3 Antibody (Center)(green, Cat#AP20845cc) compared to an isotype control of rabbit IgG(blue). AP20845c was diluted at 1:25 dilution. An Alexa Fluor® 488 goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody.

CLN3-Antibody-Center - AW5327 from Abgent, a WuXi AppTec company

Prices $110.00, $325.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of lysates from A431,KG-1 cell line,mouse kidney,mouse liver tissue lysate,SH-SY5Y cell line (from left to right), using CLN3 Antibody (Center)(Cat. #AW5327). AW5327 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.Lysates at 20ug per lane.

CLN3 antibody - GTX129457 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-CLN3 antibody used in Western blot. GTX129457
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