ALDH1B1

Gene Symbol ALDH1B1
Entrez Gene 219
Alt Symbol ALDH5, ALDHX
Species Human
Gene Type protein-coding
Description aldehyde dehydrogenase 1 family, member B1
Other Description ALDH class 2|acetaldehyde dehydrogenase 5|aldehyde dehydrogenase 5|aldehyde dehydrogenase X, mitochondrial
Swissprots P30837 B2R8F0 Q8WX76 Q9BV45
Accessions AAA96830 EAW58252 P30837 AI803741 AK225950 AK297020 BAG59552 AK313344 BAG36147 BC001619 AAH01619 BE889810 BT007418 AAP36086 DA599259 DB256700 DQ890749 ABM81675 EU176489 ABW03290 XM_011517802 XP_011516104 NM_000692 NP_000683
Function ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation.
Subcellular Location Mitochondrion matrix.
Tissue Specificity Liver, testis and to a lesser extent in brain.
Top Pathways Glycolysis / Gluconeogenesis, Tryptophan metabolism, Fatty acid degradation, Pyruvate metabolism, Glycerolipid metabolism