| Gene Symbol |
ALDH1B1
|
| Entrez Gene |
219
|
| Alt Symbol |
ALDH5, ALDHX
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
aldehyde dehydrogenase 1 family, member B1
|
| Other Description |
ALDH class 2|acetaldehyde dehydrogenase 5|aldehyde dehydrogenase 5|aldehyde dehydrogenase X, mitochondrial
|
| Swissprots |
P30837 B2R8F0 Q8WX76 Q9BV45
|
| Accessions |
AAA96830 EAW58252 P30837 AI803741 AK225950 AK297020 BAG59552 AK313344 BAG36147 BC001619 AAH01619 BE889810 BT007418 AAP36086 DA599259 DB256700 DQ890749 ABM81675 EU176489 ABW03290 XM_011517802 XP_011516104 NM_000692 NP_000683
|
| Function |
ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation.
|
| Subcellular Location |
Mitochondrion matrix.
|
| Tissue Specificity |
Liver, testis and to a lesser extent in brain.
|
| Top Pathways |
Glycolysis / Gluconeogenesis, Tryptophan metabolism, Fatty acid degradation, Pyruvate metabolism, Glycerolipid metabolism
|
![Western Blot: Aldehyde dehydrogenase 5 Overexpression Lysate (Adult Normal) [NBP2-10694] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Aldehyde dehydrogenase 5.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2265_Aldehyde%2520dehydrogenase%25205%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-10694-img0001.jpg)