| Gene Symbol |
AGTR2
|
| Entrez Gene |
186
|
| Alt Symbol |
AT2, ATGR2, MRX88
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
angiotensin II receptor, type 2
|
| Other Description |
angiotensin II type-2 receptor|type-2 angiotensin II receptor
|
| Swissprots |
Q6FGY7 Q13016 B2R9V1 P50052
|
| Accessions |
AAA50762 AAA61794 AAA84900 AAA85851 AAA98990 AAB34100 AAP72969 AAP84355 AAS45437 EAW51502 P50052 AI911273 AK313927 BAG36648 BC095504 AAH95504 CR541969 CAG46767 CR738498 DA538369 U16957 AAA67753 X87723 CAA61022 XM_011537533 XP_011535835 NM_000686 NP_000677
|
| Function |
Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation. {ECO:0000269|PubMed:15123706}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
In adult, highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. Expressed in the cerebellum. Very highly expressed in fetal kidney and intestine. {ECO:0000269|PubMed:12089445}.
|
| Top Pathways |
Adrenergic signaling in cardiomyocytes, Renin-angiotensin system, Neuroactive ligand-receptor interaction
|
![Western Blot: Angiotensin II Type 2 Receptor Overexpression Lysate (Adult Normal) [NBL1-07397] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Angiotensin II Type 2 Receptor.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7549_Angiotensin%2520II%2520Type%25202%2520Receptor%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-07397-img0002.jpg)