SOAT1

Gene Symbol SOAT1
Entrez Gene 6646
Alt Symbol ACACT, ACAT, ACAT-1, ACAT1, SOAT, STAT
Species Human
Gene Type protein-coding
Description sterol O-acyltransferase 1
Other Description acyl-coenzyme A:cholesterol acyltransferase 1|sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1
Swissprots Q5T0X4 B4DU95 A9Z1V7 P35610 Q8N1E4 A8K3P4 A6NC40
Accessions EAW91043 EAW91044 P35610 AK026611 AK290659 BAF83348 AK294047 BAG57399 AK300551 BAG62257 AK310920 AK316401 BAH14772 AL833625 BC028940 AAH28940 BQ182606 DC344271 DQ891807 ABM82733 DQ894991 ABM85917 L21934 AAC37532 XM_011509911 XP_011508213 XM_011509912 XP_011508214 NM_001252511 NP_001239440 NM_001252512 NP_001239441 NM_003101 NP_003092 NR_045530
Function Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol. Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:16154994}; Multi-pass membrane protein {ECO:0000269|PubMed:16154994}.
Top Pathways Steroid biosynthesis