| Gene Symbol | PLOD3 |
|---|---|
| Entrez Gene | 8985 |
| Alt Symbol | LH3 |
| Species | Human |
| Gene Type | protein-coding |
| Description | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 |
| Other Description | lysine hydroxylase 3|lysyl hydroxlase 3|lysyl hydroxylase 3|procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 |
| Swissprots | Q540C3 O60568 B2R6W6 |
| Accessions | AAD45831 AAF63701 CDM55391 CDM55572 EAW50205 O60568 AF046889 AAC39753 AF068229 AAC34808 AK075338 BAG52115 AK297559 BAG59952 AK298537 BAG60737 AK312743 BAG35613 AL049952 CAB43221 AY220458 AAO61775 BC011674 AAH11674 BC018946 BF941815 NM_001084 NP_001075 |
| Function | Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links. |
| Subcellular Location | Rough endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side. |
| Top Pathways | Other types of O-glycan biosynthesis, Lysine degradation |