| Gene Symbol |
PLOD3
|
| Entrez Gene |
8985
|
| Alt Symbol |
LH3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
|
| Other Description |
lysine hydroxylase 3|lysyl hydroxlase 3|lysyl hydroxylase 3|procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
|
| Swissprots |
Q540C3 O60568 B2R6W6
|
| Accessions |
AAD45831 AAF63701 CDM55391 CDM55572 EAW50205 O60568 AF046889 AAC39753 AF068229 AAC34808 AK075338 BAG52115 AK297559 BAG59952 AK298537 BAG60737 AK312743 BAG35613 AL049952 CAB43221 AY220458 AAO61775 BC011674 AAH11674 BC018946 BF941815 NM_001084 NP_001075
|
| Function |
Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links.
|
| Subcellular Location |
Rough endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side.
|
| Top Pathways |
Other types of O-glycan biosynthesis, Lysine degradation
|