VAPB

Gene Symbol VAPB
Entrez Gene 9217
Alt Symbol ALS8, VAMP-B, VAP-B
Species Human
Gene Type protein-coding
Description VAMP (vesicle-associated membrane protein)-associated protein B and C
Other Description VAMP-associated 33 kDa protein|vesicle-associated membrane protein-associated protein B/C
Swissprots O95292 A2A2F2 Q9P0H0 O95293
Accessions EAW75493 EAW75494 EAW75495 O95292 AB209665 BAD92902 AF086628 AAD13577 AF086629 AAD13578 AF160212 AAF67013 AK023241 BAG51174 AK024771 AK025720 AK123388 AK123538 BAG53909 AK124571 AK127252 BAC86901 AK128422 BAC87433 AK298036 BAG60336 AL833440 AY358464 AAQ88829 BC001712 AAH01712 BM968517 BT009811 AAP88813 DA450527 HQ447372 ADQ31858 NM_001195677 NP_001182606 NM_004738 NP_004729 NR_036633
Function Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation. {ECO:0000269|PubMed:16891305, ECO:0000269|PubMed:20940299, ECO:0000269|PubMed:22131369}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Note=Present in mitochondria-associated membranes that are endoplasmic reticulum membrane regions closely apposed to the outer mitochondrial membrane. {ECO:0000269|PubMed:22131369}.
Tissue Specificity Ubiquitous. Isoform 1 predominates.

VAP-B/C CRISPR/Cas9 KO Plasmid (h) - sc-406981 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

VAP-B/C HDR Plasmid (h) - sc-406981-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

VAP-B/C Double Nickase Plasmid (h) - sc-406981-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

VAP-B/C Double Nickase Plasmid (h2) - sc-406981-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

VAP-B/C CRISPR Activation Plasmid (h) - sc-406981-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

VAP-B/C CRISPR Activation Plasmid (h2) - sc-406981-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

VAP-B/C Lentiviral Activation Particles (h) - sc-406981-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

VAP-B/C Lentiviral Activation Particles (h2) - sc-406981-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

VAP-B/C siRNA (h) - sc-61770 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

VAP-B/C shRNA Plasmid (h) - sc-61770-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

VAP-B/C shRNA (h) Lentiviral Particles - sc-61770-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU082071 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22639 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22639 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

VAPB siRNA (Human) - CRH6101 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

VAPB - MBS8200865 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Vapb (NM_004738.4) - SHH442248 from Creative biogene

Category siRNA
Species Reactivities Human

VAPB shRNA Plasmid (Human) - CHH6101 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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