ADRB3

Gene Symbol ADRB3
Entrez Gene 155
Alt Symbol BETA3AR
Species Human
Gene Type protein-coding
Description adrenoceptor beta 3
Other Description adrenergic, beta-3-, receptor|beta-3 adrenergic receptor|beta-3 adrenoceptor|beta-3 adrenoreceptor
Swissprots P13945 Q4JFT4
Accessions AAA35550 AAY88743 CAA50142 CAA50143 CAA51383 EAW63343 EAW63344 P13945 AK293033 BAF85722 AK309919 AK313857 BAG36585 AY487247 AAR37414 BC075017 AAH75017 BQ024407 DA904248 FJ170286 ACL14174 FJ170287 ACL14175 S53291 AAB24837 X70811 CAA50141 NM_000025 NP_000016
Function Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Expressed mainly in adipose tissues.
Top Pathways Calcium signaling pathway, Endocytosis, Salivary secretion, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction