| Gene Symbol |
ADRB3
|
| Entrez Gene |
155
|
| Alt Symbol |
BETA3AR
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
adrenoceptor beta 3
|
| Other Description |
adrenergic, beta-3-, receptor|beta-3 adrenergic receptor|beta-3 adrenoceptor|beta-3 adrenoreceptor
|
| Swissprots |
P13945 Q4JFT4
|
| Accessions |
AAA35550 AAY88743 CAA50142 CAA50143 CAA51383 EAW63343 EAW63344 P13945 AK293033 BAF85722 AK309919 AK313857 BAG36585 AY487247 AAR37414 BC075017 AAH75017 BQ024407 DA904248 FJ170286 ACL14174 FJ170287 ACL14175 S53291 AAB24837 X70811 CAA50141 NM_000025 NP_000016
|
| Function |
Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expressed mainly in adipose tissues.
|
| Top Pathways |
Calcium signaling pathway, Endocytosis, Salivary secretion, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction
|