| Gene Symbol |
Slc2a8
|
| Entrez Gene |
85256
|
| Alt Symbol |
Glut8
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 2, (facilitated glucose transporter) member 8
|
| Other Description |
GLUT-8|glucose transporter type 8|glucose transporter type X1|solute carrier family 2, facilitated glucose transporter member 8
|
| Swissprots |
Q9JMA6 Q9JJZ1
|
| Accessions |
EDL93196 EDL93197 Q9JJZ1 AJ245935 CAB75729 BU759499 XM_008761779 XP_008760001 NM_053494 NP_445946
|
| Function |
Insulin-regulated facilitative glucose transporter. Binds cytochalasin B in a glucose-inhibitable manner. Seems to be a dual-specific sugar transporter as it is inhibitable by fructose.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Principally intracellular. May move between intracellular vesicles and the plasma membrane. The dileucine internalization motif is critical for intracellular sequestration.
|
| Tissue Specificity |
Highly expressed in adult and pubertal testis, but not prepubertal testis. Moderate expression in hypothalamus, cerebellum, brainstem, hippocampus, and adrenal gland. Lower amounts present in most other tissues. {ECO:0000269|PubMed:10821868}.
|