PI4KB

Gene Symbol	PI4KB
Entrez Gene	5298
Alt Symbol	NPIK, PI4K-BETA, PI4K92, PI4KBETA, PI4KIIIBETA, PIK4CB
Species	Human
Gene Type	protein-coding
Description	phosphatidylinositol 4-kinase, catalytic, beta
Other Description	PtdIns 4-kinase beta|phosphatidylinositol 4-kinase beta|phosphatidylinositol 4-kinase, wortmannin-sensitive|type III phosphatidylinositol 4-kinase beta
Swissprots	Q5VWB9 P78405 Q9BWR6 B4DGI2 Q9UBF8 Q5VWC0 O15096 Q5VWC1
Accessions	CAC69371 EAW53449 EAW53450 Q9UBF8 AB005910 BAA21661 AJ011121 CAA09495 AK054691 AK294606 BAG57793 AK311292 AL832188 BC000029 AAH00029 BC040300 AAH40300 DC350175 DC365634 U81802 AAC51156 XM_005245264 XP_005245321 XM_011509634 XP_011507936 XM_011509635 XP_011507937 XM_011509636 XP_011507938 XM_011509637 XP_011507939 XM_011509638 XP_011507940 NM_001198773 NP_001185702 NM_001198774 NP_001185703 NM_001198775 NP_001185704 NM_002651 NP_002642
Function	Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking (By similarity). {ECO:0000250}.
Subcellular Location	Endomembrane system. Mitochondrion outer membrane; Peripheral membrane protein. Rough endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus. Cytoplasm, perinuclear region. Note=Found in the outer membrane of mitochondria and membranes of the rough endoplasmic reticulum. Recruited to the Golgi complex by the small GTPase ARF to stimulate the synthesis of phosphatidylinositol 4,5-bisphosphate (PIP2) on the Golgi complex.
Tissue Specificity	Widely expressed with highest levels in heart, skeletal muscle, pancreas, testis and ovary. Weakly expressed in liver. {ECO:0000269|PubMed:9020160, ECO:0000269|PubMed:9405935, ECO:0000269|PubMed:9405938}.
Top Pathways	Inositol phosphate metabolism, Phosphatidylinositol signaling system

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PI4KB Gene cDNA Clone - orb144734 from Biorbyt Prices $366.00 Sizes 10 μg Species Human

Human-PI4KB-cDNA-Clone - DC00012 from Abgent, a WuXi AppTec company Prices $1,081.35 Sizes 10 µg Species Human Accession BC000029

PI4KB - MBS1269636 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC000029

Human PI4KB Gene ORF cDNA clone in cloning vector - HG15004-G from Sino Biological Species Human

Human PI4KB Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG15004-ACG from Sino Biological Species Human

Human PI4KB Gene ORF cDNA clone expression plasmid, N-Flag tag - HG15004-NF from Sino Biological Species Human

Human PI4KB Gene ORF cDNA clone expression plasmid, N-HA tag - HG15004-NY from Sino Biological Species Human

Human PI4KB Gene ORF cDNA clone expression plasmid, N-His tag - HG15004-NH from Sino Biological Species Human

Human PI4KB Gene ORF cDNA clone expression plasmid, C-Flag tag - HG15004-CF from Sino Biological Species Human

Human PI4KB Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG15004-ACR from Sino Biological Species Human

Human PI4KB Gene ORF cDNA clone expression plasmid, N-Myc tag - HG15004-NM from Sino Biological Species Human

Human PI4KB Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG15004-ANR from Sino Biological Species Human

Human PI4KB Gene ORF cDNA clone expression plasmid, C-Myc tag - HG15004-CM from Sino Biological Species Human

Human PI4KB Gene ORF cDNA clone expression plasmid - HG15004-UT from Sino Biological Species Human

Human PI4KB Gene ORF cDNA clone expression plasmid, C-His tag - HG15004-CH from Sino Biological Species Human

Human PI4KB Gene ORF cDNA clone expression plasmid, C-HA tag - HG15004-CY from Sino Biological Species Human

Human PI4KB Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG15004-ANG from Sino Biological Species Human

Human PI4KB ORF Clone(NM_001198773.1) - CDCR358956 from Creative biogene Species Human

Human PI4KB ORF clone (NM_001198775.1) - CDCL149055 from Creative biogene Species Human

Human PI4KB ORF Clone (BC000029) - CDCS409385 from Creative biogene Species Human Accession Q9UBF8

Human PI4KB ORF clone (BC000029) - CDCB158525 from Creative biogene Species Human

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