KCNN2

Gene Symbol KCNN2
Entrez Gene 3781
Alt Symbol KCa2.2, SK2, SKCA2, SKCa 2, hSK2
Species Human
Gene Type protein-coding
Description potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
Other Description apamin-sensitive small-conductance Ca2+-activated potassium channel|potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2|small conductance calcium-activated potassium channel 2|small conductance calcium-activated potassium channel protein 2
Swissprots Q6X2Y2 Q0VFZ4 Q6PJI0 A6NF94 Q9H2S1
Accessions EAW48975 EAW48976 Q9H2S1 AF239613 AAG16728 AF397175 AAK84039 AK090521 AK289948 BAF82637 AY258141 AAP45946 BC015371 AAH15371 BC040722 BC117454 AAI17455 BC117456 AAI17457 BG477734 BG769522 XM_011543387 XP_011541689 XM_011543388 XP_011541690 XM_011543389 XP_011541691 NM_001278204 NP_001265133 NM_021614 NP_067627 NM_170775 NP_740721 NR_103458
Function Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Expressed in atrial myocytes (at protein level). Widely expressed. {ECO:0000269|PubMed:13679367}.
Top Pathways Bile secretion

KCNN2 peptide - ab186680 from Abcam

Category Peptide

KCNN2 Antibody Blocking Peptide - LS-E27193 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

KCNN2 Antibody Blocking Peptide - LS-E12489 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

KCNN2 Antibody Blocking Peptide - LS-E29693 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 50 µg

KCNN2 blocking peptide - GTX88269-PEP from GeneTex

Category Peptide
Prices $239.00
Sizes 100 μg
Species Human, Mouse, Dog, Rat, Bovine

KCNN2 Blocking Peptide - 33R-4564 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

KCNN2 Blocking Peptide - 33R-3914 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

KCNN2 Peptide - AC21-2013-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

KCNN2 Peptide - 42-239P from ProSci

Category Peptide
Prices $175.00
Sizes 100 µg
Species Human
Western blot analysis of KCNN2 in Human Liver Lysate (35 μg protein in ripa buffer) using KCNN2 antibody (0.3 μg/mL).

KCNN2, Peptide - MBS425445 from MyBioSource

Category Peptide
Prices $175.00
Sizes 100 µg
Species Human, Mouse, Rat, Dog, Bovine

KCNN2 Recombinant Protein Antigen - NBP1-83187PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

KCNN2 Peptide, Human - M34GP07996H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Small conductance calcium-activated potassium channel protein 2 (KCNN2), Recombinant Protein - MBS7100747 from MyBioSource

Category Protein
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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