CYP2C19

Gene Symbol CYP2C19
Entrez Gene 1557
Alt Symbol CPCJ, CYP2C, CYPIIC17, CYPIIC19, P450C2C, P450IIC19
Species Human
Gene Type protein-coding
Description cytochrome P450, family 2, subfamily C, polypeptide 19
Other Description (R)-limonene 6-monooxygenase|(S)-limonene 6-monooxygenase|(S)-limonene 7-monooxygenase|S-mephenytoin 4-hydroxylase|cytochrome P-450 II C|cytochrome P450 2C19|cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19|cytochrome P450-11A|cytochrome P450-254C|flavoprotein-linked monooxygenase|mephenytoin 4'-hydroxylase|mephenytoin 4-hydroxylase|microsomal monooxygenase|xenobiotic monooxygenase
Swissprots Q8WZB1 Q9UCD4 P33259 Q8WZB2 P33261
Accessions AAL31347 AAL31348 AAV41877 ABZ69068 ABZ69069 ABZ69070 ABZ69071 ABZ69072 ABZ69073 ABZ69074 ABZ69075 ABZ69076 ABZ69077 ABZ69078 ABZ69079 ABZ69080 ABZ69081 ABZ69082 ABZ69083 ABZ69084 ABZ69085 ABZ69086 ABZ69087 ABZ69088 ABZ69089 ABZ69090 ABZ69091 ABZ69092 ABZ69093 ABZ69094 ABZ69095 ABZ69096 ABZ69097 ABZ69098 ABZ69099 ABZ69100 ABZ69101 ABZ69102 ABZ69103 ABZ69104 ABZ69105 ABZ69106 ABZ69107 ABZ69108 ABZ69109 ABZ69110 ABZ69111 ABZ69112 ABZ69113 ABZ69114 ABZ69115 ABZ69116 ABZ69117 ABZ69118 ABZ69119 ABZ69120 ABZ69121 ABZ69122 ABZ69123 ABZ69124 ABZ69125 BAD02827 P33261 BC111846 AAI11847 CB158473 CB161988 M61854 AAB59426 X65962 CAA46778 NM_000769 NP_000760
Function Responsible for the metabolism of a number of therapeutic agents such as the anticonvulsant drug S-mephenytoin, omeprazole, proguanil, certain barbiturates, diazepam, propranolol, citalopram and imipramine.
Subcellular Location Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Top Pathways Chemical carcinogenesis, Arachidonic acid metabolism, Linoleic acid metabolism, Drug metabolism - cytochrome P450

CYP2C8/9/18/19 (K-21) - sc-23435 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CYP2C8/9/18/19 (K-21): sc-23435. Immunoperoxidase staining of formalin fixed, paraffin-embedded human liver tissue showing cytoplasmic staining of hepatocytes.

CYP2C9/19 (C-21) - sc-23436 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CYP2C9/19 (C-21): sc-23436. Immunoperoxidase staining of formalin fixed, paraffin-embedded human liver tissue showing cytoplasmic staining of hepatocytes.

Anti-CYP2C19 antibody [EPR6576] - ab137015 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6576
All lanes : Anti-CYP2C19 antibody [EPR6576] (ab137015) at 1/1000 dilutionLane 1 : Mouse liver lysateLane 2 : Rat liver lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-Cytochrome p450 2C19 antibody - ab83233 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Cytochrome p450 2C19 antibody (ab83233) at 1 µg/ml + placental lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-Cytochrome p450 2C19 antibody - ab135785 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Cytochrome p450 2C19 antibody (ab135785) at 1/50 dilution + Jurkat cell line lysate at 35 µg

Anti-Cytochrome p450 2C19 antibody - ab95360 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Cytochrome p450 2C19 antibody (ab95360) + HL-60 cell line lysates at 35 µg

Anti-Cytochrome p450 2C19 antibody - ab136120 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Cytochrome p450 2C19 antibody [EPR6577] - C-terminal - ab185213 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6577
Immunoprecipitation analysis of 293 cell lysate immunoprecipitated for Cytochrome P450 2C19 using ab185213 at 1/50 dilution (Lane 1). A aAnti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1500 dilution was used as secondary. Lane 2: PBS instead of 293 lysates

Anti-Cytochrome P450 2C8 + 2C9 + 2C18 + 2C19 antibody - ab72598 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cytochrome P450 2C8 + 2C9 + 2C18 + 2C19 antibody (ab72598) at 1/500 dilutionLane 1 : Extracts from LOVO cellsLane 2 : Extracts from LOVO cells with immunising peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-Cytochrome P450 2C8 + 2C9 + 2C19 + 2C12 antibody - ab22596 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of frozen Human heart tissue, staining Cytochrome P450 2C8 + 2C9 + 2C19 + 2C12 with ab22596. A biotinylated anti-rabbit IgG was used as the secondary antibody. Staining was detected using DAB.

Anti-Cytochrome P450 2C8 + 2C9 + 2C19 + 2C12 antibody - C-terminal - ab195660 from Abcam

Prices $370.00
Sizes 25 µl
Host Rabbit
Clonality Polyclonal

Anti-CYP2C19 Antibody (Lys270) - LS-C177035 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
IHC of CYP2C19 (K270) pAb in paraffin-embedded human liver carcinoma tissue.

Anti-CYP2C19 Antibody (aa264-293) - LS-C167222 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CYP2C19 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-CYP2C19 Antibody (aa88-117) - LS-C167223 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with CYP2C19 Antibody ,which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-CYP2C19 Antibody - LS-C6341 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP2C19 Antibody (aa221-270) - LS-C291855 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP2C19 Antibody (aa324-373) - LS-C110653 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CYP2C19 antibody LS-C110653 Western blot of Placenta lysate.

Anti-CYP2C19 Antibody (aa241-290) - LS-C119498 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of extracts from 293 cells, using Cytochrome P450 2C19 Antibody. The lane on the right is treated with the synthesized peptide.

Cytochrome P450 2C19 Antibody - NBP1-85488 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-CYP2C19 Polyclonal Antibody - bs-2795R from Bioss

Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti CYP2C19 Polyclonal Antibody (bs-2795R), Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining

Anti-CYP2C19 antibody produced in rabbit - SAB2100520 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CYP2C19: <B>Cat. No.SAB2100520</B>: CYP2C19 in Placenta tissue lysate with CYP2C19 antibody at 1.0 μg/mL.

Anti-CYP2C19 antibody produced in rabbit - HPA015066 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CYP2C19: <B>Cat. No. HPA015066</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human liver shows strong cytoplasmic positivity in hepatocytes.

Anti-Cytochrome P450 2C19 antibody produced in rabbit - SAB4500590 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-Cytochrome P450 2C19: <B>Cat. No. SAB4500590</B>: Immunoblotting analysis of extracts from 293 cells, using Anti-Cytochrome P450 2C19 antibody. The lane on the left was treated with the Anti-Cytochrome P450 2C19 antibody. The lane on the right (negative control) was treated with both Anti-Cytochrome P450 2C19 antibody and the synthesized immunogen peptide.

CYP2C19 antibody - middle region (ARP41807_P050) - ARP41807_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CYP2C19-Antibody-Center - AP6710c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of CYP2C19 Antibody (Center) (Cat. #AP6710c) in Jurkat cell line lysates (35ug/lane). CYP2C19 (arrow) was detected using the purified Pab.
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