| Gene Symbol |
WNT2
|
| Entrez Gene |
7472
|
| Alt Symbol |
INT1L1, IRP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
wingless-type MMTV integration site family member 2
|
| Other Description |
Int-1-related protein|int-1-like protein 1|protein Wnt-2|secreted growth factor
|
| Swissprots |
A4D0V1 Q75N05 Q9UDP9 P09544
|
| Accessions |
AAB67043 AAD28351 CAI38640 CCQ43213 EAL24355 EAW83525 P09544 AK056742 BAG51800 BC029854 AAH29854 BC078170 AAH78170 BT019608 AAV38415 DQ892457 ABM83383 DQ895669 ABM86595 X07876 CAA30725 NM_003391 NP_003382 NR_024047
|
| Function |
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix.
|
| Tissue Specificity |
Expressed in brain in the thalamus, in fetal and adult lung and in placenta. {ECO:0000269|PubMed:11449391}.
|
| Top Pathways |
Proteoglycans in cancer, Wnt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Hippo signaling pathway, HTLV-I infection
|
![Western Blot: WNT2 Overexpression Lysate (Adult Normal) [NBL1-17866] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for WNT2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7533_WNT2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-17866-img0002.jpg)