ITGB4

Gene Symbol	ITGB4
Entrez Gene	3691
Alt Symbol	CD104
Species	Human
Gene Type	protein-coding
Description	integrin, beta 4
Other Description	CD104 antigen|GP150|integrin beta-4|integrin beta-4 subunit
Swissprots	O15339 O14691 A0AVL6 Q0VF97 O15341 O15340 P16144 Q9UIQ4 O14690
Accessions	AAB65422 AAC51632 AAC51633 AAC51634 CAB61345 EAW89305 EAW89306 EAW89307 EAW89308 EAW89309 EAW89310 EAW89311 EAW89312 EAW89313 EAW89314 EAW89315 P16144 AB208913 BAD92150 AF011375 AAB65421 AI318403 AK304792 BAG65542 AK310952 BC109238 AAI09239 BC118916 AAI18917 BC126411 AAI26412 BC143738 AAI43739 BC143742 AAI43743 CA391583 X51841 CAA36134 X52186 CAA36433 X53587 CAA37656 XM_005257309 XP_005257366 XM_005257311 XP_005257368 XM_005257312 XP_005257369 XM_006721866 XP_006721929 XM_006721867 XP_006721930 XM_006721868 XP_006721931 XM_006721870 XP_006721933 XM_011524751 XP_011523053 XM_011524752 XP_011523054 NM_000213 NP_000204 NM_001005619 NP_001005619 NM_001005731 NP_001005731
Function	Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. {ECO:0000269|PubMed:12482924, ECO:0000269|PubMed:19403692}.
Subcellular Location	Cell membrane; Single-pass type I membrane protein. Cell membrane; Lipid-anchor. Cell junction, hemidesmosome. Note=Colocalizes with DST at the leading edge of migrating keratinocytes.
Tissue Specificity	Integrin alpha-6/beta-4 is predominantly expressed by epithelia. Isoform beta-4D is also expressed in colon and placenta. Isoform beta-4E is also expressed in epidermis, lung, duodenum, heart, spleen and stomach.
Top Pathways	Focal adhesion, ECM-receptor interaction, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ITGB4 transcript variant 2 Gene cDNA Clone - orb143904 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Human Integrin beta 4/CD104 (NP_001005731) VersaClone cDNA - RDC0958 from R&D Systems Prices $799.00 Sizes 10 µg Species Human

Human Integrin beta 4/CD104 (NP_000204) VersaClone cDNA - RDC1079 from R&D Systems Prices $799.00 Sizes 10 µg Species Human

Human ITGB4 cDNA clone(NM_000213.3) - CDFH009455 from Creative Biomart Species Human Accession NM_000213.3

Human ITGB4 cDNA clone(NM_001005619.1) - CDFH009456 from Creative Biomart Species Human Accession NM_001005619.1

Human ITGB4 cDNA clone(NM_001005731.1) - CDFH009457 from Creative Biomart Species Human Accession NM_001005731.1

Human ITGB4 ORF clone(NM_001005619.1) - CDCL184994 from Creative Biomart Species Human Accession NM_001005619.1

Human ITGB4 ORF Clone(NM_000213.3) - CDCR279201 from Creative Biomart Species Human Accession NM_000213.3

Human ITGB4 ORF Clone(NM_000213.3) - CDCR279202 from Creative Biomart Species Human Accession NM_000213.3

Human ITGB4 ORF Clone(NM_001005619.1) - CDCR339886 from Creative Biomart Species Human Accession NM_001005619.1

Human ITGB4 ORF Clone(NM_001005619.1) - CDCR339887 from Creative Biomart Species Human Accession NM_001005619.1

Human ITGB4 ORF Clone(NM_001005731.1) - CDCR339888 from Creative Biomart Species Human Accession NM_001005731.1

Human ITGB4 ORF Clone(NM_001005731.1) - CDCR339889 from Creative Biomart Species Human Accession NM_001005731.1

Human Integrin beta 4/CD104 transcript variant 2 Gene ORF cDNA clone in cloning vector - HG13512-G from Sino Biological Species Human

Human Integrin beta 4/CD104 transcript variant 2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13512-NM from Sino Biological Species Human

Human Integrin beta 4/CD104 transcript variant 2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13512-CF from Sino Biological Species Human

Human Integrin beta 4/CD104 transcript variant 2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13512-ACG from Sino Biological Species Human

Human Integrin beta 4/CD104 transcript variant 2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG13512-CY from Sino Biological Species Human

Human Integrin beta 4/CD104 transcript variant 2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13512-CM from Sino Biological Species Human

Human Integrin beta 4/CD104 transcript variant 2 Gene ORF cDNA clone expression plasmid, N-His tag - HG13512-NH from Sino Biological Species Human

Human Integrin beta 4/CD104 transcript variant 2 Gene ORF cDNA clone expression plasmid - HG13512-UT from Sino Biological Species Human

Human Integrin beta 4/CD104 transcript variant 2 Gene ORF cDNA clone expression plasmid, C-His tag - HG13512-CH from Sino Biological Species Human

Human Integrin beta 4/CD104 transcript variant 2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13512-ACR from Sino Biological Species Human

Human Integrin beta 4/CD104 transcript variant 2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG13512-NY from Sino Biological Species Human

Human Integrin beta 4/CD104 transcript variant 2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13512-NF from Sino Biological Species Human

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