HSD17B4

Gene Symbol HSD17B4
Entrez Gene 3295
Alt Symbol DBP, MFE-2, MPF-2, PRLTS1, SDR8C1
Species Human
Gene Type protein-coding
Description hydroxysteroid (17-beta) dehydrogenase 4
Other Description 17-beta-HSD 4|17-beta-HSD IV|17-beta-hydroxysteroid dehydrogenase 4|17beta-estradiol dehydrogenase type IV|3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase|D-3-hydroxyacyl-CoA dehydratase|D-bifunctional protein, peroxisomal|beta-hydroxyacyl dehydrogenase|beta-keto-reductase|multifunctional protein 2|peroxisomal multifunctional enzyme type 2|peroxisomal multifunctional protein 2|short chain dehydrogenase/reductase family 8C member 1|short chain dehydrogenase/reductase family 8C, member 1
Swissprots F5HE57 B4DNV1 E9PB82 P51659 B4DVS5
Accessions AAD08652 CAA72203 EAW48910 EAW48911 P51659 AK094049 BAG52804 AK293254 BAG56786 AK295440 BAG58380 AK298075 BAG60363 AK299685 BAG61592 AK301212 BAG62787 AK308968 AK312449 BAG35356 AL713635 AU105854 BC003098 AAH03098 CB067275 CX782401 DA296575 DA426062 DA508630 DC325873 DQ891866 ABM82792 DQ895055 ABM85981 X87176 CAA60643 NM_001199291 NP_001186220 NM_001292027 NP_001278956 NM_001292028 NP_001278957 NM_000414 NP_000405 NM_001199292 NP_001186221
Function Bifunctional enzyme acting on the peroxisomal beta- oxidation pathway for fatty acids. Catalyzes the formation of 3- ketoacyl-CoA intermediates from both straight-chain and 2-methyl- branched-chain fatty acids. {ECO:0000269|PubMed:8902629, ECO:0000269|PubMed:9089413}.
Subcellular Location Peroxisome.
Tissue Specificity Present in many tissues with highest concentrations in liver, heart, prostate and testis.
Top Pathways Primary bile acid biosynthesis, Peroxisome

17β-HSD4 (T-20) - sc-66423 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-hydroxysteroid (17-beta) dehydrogenase 4 antibody - ab97971 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-hydroxysteroid (17-beta) dehydrogenase 4 antibody (ab97971) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

Anti-hydroxysteroid (17-beta) dehydrogenase 4 antibody - ab97975 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-hydroxysteroid (17-beta) dehydrogenase 4 antibody (ab97975) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

Anti-Hydroxysteroid (17-beta) Dehydrogenase 4 antibody - ab113070 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Hydroxysteroid (17-beta) Dehydrogenase 4 antibody (ab113070) at 1/100 dilution + NCI-H292 cell line lysate at 35 µg

Anti-Hydroxysteroid (17-beta) Dehydrogenase 4 antibody [2D3BB5BF10] - ab128565 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2D3BB5BF10
Immunoprecipitation using ab128565. The protein is found both as a full length peptide and in a cleaved version. Lane 1: Ladder Lane 2: Human Liver Homogenate.

Anti-Hydroxysteroid (17-beta) Dehydrogenase 4 antibody [2D3BB5BF10] (Alexa Fluor® 488) - ab198591 from Abcam

Prices $425.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2D3BB5BF10
ab198591 staining Hydroxysteroid (17-beta) Dehydrogenase 4 in HepG2 cells. The cells were fixed with 4% formaldehyde (10 min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab198591 at 1/100 dilution (shown in red) and ab195889, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 594), at 1/250 dilution (shown in green). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Anti-Hydroxysteroid (17-beta) Dehydrogenase 4 antibody [2D3BB5BF10] (Alexa Fluor® 647) - ab198320 from Abcam

Prices $425.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2D3BB5BF10
ab198320 staining Hydroxysteroid (17-beta) Dehydrogenase 4 in HepG2 cells. The cells were fixed with 4% formaldehyde (10 min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1%PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab198320 at 1/100 dilution (shown in red) and ab195887, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 488), at 1/250 dilution (shown in green). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Anti-Hydroxysteroid (17-beta) Dehydrogenase 4 antibody [3C5] - ab180368 from Abcam

Prices $357.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3C5
All lanes : Anti-Hydroxysteroid (17-beta) Dehydrogenase 4 antibody [3C5] (ab180368) at 1/4000 dilutionLane 1 : Non-transfected HEK293T cell lysateLane 2 : Hydroxysteroid (17-beta) Dehydrogenase 4 transfected HEK293T cell lysateLysates/proteins at 5 µg per lane.

Anti-Hydroxysteroid (17-beta) Dehydrogenase 4 antibody [8E5AB11] - ab110297 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 8E5AB11
Immunoprecipitation with ab110297 from Human Liver Microsomes.

Anti-Hydroxysteroid (17-beta) Dehydrogenase 4 antibody [EPR12175] - ab170910 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR12175
Flow cytometric analysis of permeabilized K562 cells labeling Hydroxysteroid (17-beta) Dehydrogenase 4 using ab170910 at 1/10 dilution (red) or a rabbit IgG negative (green).

Anti-Hydroxysteroid (17-beta) Dehydrogenase 4 antibody - N-terminal - ab190558 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Hydroxysteroid (17-beta) Dehydrogenase 4 antibody - N-terminal (ab190558) at 1/500 dilutionLane 1 : K562 cell extractLane 2 : HuvEc cell extractLysates/proteins at 30 µg per lane.

Anti-HSD17B4 Antibody (clone 2C9) - LS-C338357 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2C9
IHC of paraffin-embedded Human liver tissue using anti-HSD17B4 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).

Anti-HSD17B4 Antibody (aa18-261) - LS-C186386 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded OVCA using HSD17B4 antibody at 1:500 dilution.

Anti-HSD17B4 Antibody (clone 1F3) - LS-C338333 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1F3
IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-HSD17B4 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).

Anti-HSD17B4 Antibody (aa744-761) - LS-C312878 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
HSD17B4 antibody. IHC(P): Human Intestinal Cancer Tissue.

Anti-HSD17B4 Antibody - LS-C153198 from LifeSpan Bioscience

Prices $410.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HSD17B4 Antibody - LS-C153199 from LifeSpan Bioscience

Prices $410.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HSD17B4 Antibody (aa134) - LS-C190207 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-HSD17B4 Antibody (aa134) - LS-C190208 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-HSD17B4 Antibody (aa341-370, AP) - LS-C215186 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HSD17B4 Antibody (aa341-370, APC) - LS-C215187 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HSD17B4 Antibody (aa341-370, Biotin) - LS-C215188 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HSD17B4 Antibody (aa341-370, Azide-free, HRP) - LS-C215189 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HSD17B4 Antibody (aa341-370, FITC) - LS-C215190 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HSD17B4 Antibody (aa341-370, PE) - LS-C215191 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Search more