| Gene Symbol |
GUCY2D
|
| Entrez Gene |
3000
|
| Alt Symbol |
CORD5, CORD6, CYGD, GUC1A4, GUC2D, LCA, LCA1, RCD2, RETGC-1, ROS-GC1, ROSGC, retGC
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
guanylate cyclase 2D, membrane (retina-specific)
|
| Other Description |
ROS-GC|cone rod dystrophy 6|guanylate cyclase 2D, retinal|retinal guanylate cyclase 1|retinal guanylyl cyclase 1|rod outer segment membrane guanylate cyclase
|
| Swissprots |
Q02846 Q6LEA7
|
| Accessions |
AAA60366 CAA10914 EAW90103 Q02846 BC148421 AAI48422 BM931704 DQ426876 ABD90536 M92432 AAA60547 XM_011523816 XP_011522118 NM_000180 NP_000171
|
| Function |
Probably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction.
|
| Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
| Tissue Specificity |
Retina. Localized exclusively in the nuclei and inner segments of the rod and cone photoreceptor cells.
|
| Top Pathways |
Olfactory transduction, Phototransduction, Purine metabolism
|