POLE2

Gene Symbol POLE2
Entrez Gene 5427
Alt Symbol DPE2
Species Human
Gene Type protein-coding
Description polymerase (DNA directed), epsilon 2, accessory subunit
Other Description DNA polymerase II subunit 2|DNA polymerase epsilon subunit 2|DNA polymerase epsilon subunit B|polymerase (DNA directed), epsilon 2 (p59 subunit)
Swissprots O43560 P56282 A4LBB7 B4DDE6 A6NH58 A4FU92 A0AV55
Accessions AAK72254 ABO43040 EAW65754 P56282 AF025840 AAC51920 AF036899 AAC39610 AK293163 BAG56707 AK314963 BC112962 AAI12963 BC126218 AAI26219 BC126220 AAI26221 BG189206 BX248064 CAD62358 HQ258453 ADR83207 XM_011536841 XP_011535143 XM_011536842 XP_011535144 XM_011536843 XP_011535145 XM_011536844 XP_011535146 XR_943479 XR_943480 NM_001197330 NP_001184259 NM_001197331 NP_001184260 NM_002692 NP_002683
Function Participates in DNA repair and in chromosomal DNA replication.
Subcellular Location Nucleus.
Top Pathways DNA replication, Base excision repair, Nucleotide excision repair, HTLV-I infection, Purine metabolism

DNA pol ε B (N-18) - sc-8804 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

DNA pol ε B (C-17) - sc-8805 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DNA pol ε B (C-17): sc-8805. Western blot analysis of DNA pol ε B expression in SK-N-SH whole cell lysate.

Anti-DNA Polymerase epsilon p59 antibody - ab57298 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Overlay histogram showing HeLa cells stained with ab57298 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab57298, 0.1μg/1x106 cells) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-mouse IgG (H&L) (ab150113) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.

Anti-POLE2 Antibody (aa1-101, Azide-free) - LS-C330592 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-POLE2 Antibody (aa144-189) - LS-C313743 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-POLE2 Antibody (aa495-523) - LS-C203876 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
POLE2 Antibody western blot of HL-60 cell line lysates (35 ug/lane). The POLE2 antibody detected the POLE2 protein (arrow).

Anti-POLE2 Antibody (clone 1A3) - LS-C197941 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1A3
POLE2 monoclonal antibody (M01), clone 1A3. Western Blot analysis of POLE2 expression in Raw 264.7.

DNA Polymerase epsilon p59 Antibody - NBP1-87970 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DNA Polymerase epsilon p59 Antibody (1A3) - H00005427-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1A3
Western Blot: DNA Polymerase epsilon p59 Antibody (1A3) [H00005427-M01] - POLE2 monoclonal antibody (M01), clone 1A3. Analysis of POLE2 expression in Raw 264.7.

DNA Polymerase epsilon p59 Antibody - H00005427-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

POLE2 Polyclonal Antibody - bs-14356R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded mouse embryo labeled with Rabbit Anti-POLE2 Polyclonal Antibody, Unconjugated (bs-14356R) at 1:200 followed by conjugation to the secondary antibody and DAB staining\\n

Anti-POLE2 antibody produced in rabbit - HPA027555 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-POLE2: <B>Cat. No. HPA027555</B>: Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in exocrine cells.

Monoclonal Anti-POLE2 antibody produced in mouse - WH0005427M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1A3
<B>Immunoblotting</B><BR/>Monoclonal Anti-POLE2, <B>Cat. No. WH0005427M1</B> used at the antibody concentration: 1 ~ 5 μg/mL. Specific band of ~59.5 kDa using Hela NE lysate.

ANTI-POLE2(C-TERMINAL) antibody produced in rabbit - SAB1307265 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-POLE2 (C-term): <B>Cat. No. SAB1307265</B>: POLE2 Antibody (C-term) western blot analysis in HL-60 cell line lysates (35 μg/lane).

POLE2-Antibody-monoclonal-M01 - AT3369a from Abgent, a WuXi AppTec company

Prices $315.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1A3
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .

POLE2-Antibody-C-term - AP20396b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
POLE2 Antibody (C-term) (Cat. #AP20396b) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the POLE2 antibody detected the POLE2 protein (arrow).

POLE2 Antibody - C-terminal region (OAAB17923) - OAAB17923 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

POLE2 Antibody (OABF00696) - OABF00696 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

POLE2 Antibody - abx034739 from Abbexa

Host Rabbit
Clonality Polyclonal

POLE2 antibody - H00005427-M01 from Acris Antibodies

Prices $360.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1A3
POLE2 monoclonal antibody (M01), clone 1A3. Western Blot analysis of POLE2 expression in PC-12 ( Cat # L012V1 ).

POLE2 antibody - H00005427-A01 from Acris Antibodies

Prices $300.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

POLE2 antibody - H00005427-B01P from Acris Antibodies

Prices $1,530.00
Sizes 500 µg
Host Mouse
Clonality Polyclonal

Rabbit Anti-Human POLE2 (C-term) - 102-14736 from RayBiotech

Host Rabbit

POLE2 antibody (C-term) - STJ48169 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal
Clone RB42913
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