| Gene Symbol |
PLB1
|
| Entrez Gene |
100009309
|
| Alt Symbol |
PHLPB
|
| Species |
Rabbit
|
| Gene Type |
protein-coding
|
| Description |
phospholipase B1
|
| Other Description |
PLB/LIP|phospholipase AdRab-B|phospholipase B|phospholipase B/lipase|phospholipase B1, membrane-associated
|
| Swissprots |
Q05017
|
| Accessions |
Q05017 Z12841 CAA78303 NM_001101708 NP_001095178
|
| Function |
Membrane-associated phospholipase. Exhibits a calcium- independent broad substrate specificity including phospholipase A2/lysophospholipase activity. Can convert phosphatidylcholine to fatty acids and glycerophosphocholine. Could be involved in uptake of dietary lipids, possibly including long chain retinyl esters. {ECO:0000269|PubMed:8509424}.
|
| Subcellular Location |
Apical cell membrane {ECO:0000250}; Single- pass type I membrane protein {ECO:0000250}. Note=Present in the intestinal brush border membranes.
|
| Tissue Specificity |
Intestine. {ECO:0000269|PubMed:8509424}.
|
| Top Pathways |
Vitamin digestion and absorption, Glycerophospholipid metabolism, Ether lipid metabolism, Arachidonic acid metabolism, Linoleic acid metabolism
|