| Gene Symbol |
SERPINF2
|
| Entrez Gene |
5345
|
| Alt Symbol |
A2AP, AAP, ALPHA-2-PI, API, PLI
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
|
| Other Description |
alpha-2-AP|alpha-2-antiplasmin|alpha-2-plasmin inhibitor|serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2|serpin F2
|
| Swissprots |
Q9UCG2 Q8N5U7 B4E1B7 P08697 Q9UCG3
|
| Accessions |
AAA51554 AAA51555 EAW90578 EAW90579 EAW90580 EAW90581 P08697 AK303763 BAG64729 AL564784 BC031592 AAH31592 BX107460 CK300825 D00116 BAA00070 D00174 BAA00124 DQ890796 ABM81722 DQ893951 ABM84877 J02654 AAA35543 XM_005256699 XP_005256756 XM_005256700 XP_005256757 XM_005256701 XP_005256758 XM_005256703 XP_005256760 XM_011546754 XP_011545056 XM_011546755 XP_011545057 XM_011546756 XP_011545058 NM_000934 NP_000925 NM_001165920 NP_001159392 NM_001165921 NP_001159393
|
| Function |
Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin. {ECO:0000269|PubMed:15853774}.
|
| Subcellular Location |
Secreted.
|
| Tissue Specificity |
Expressed by the liver and secreted in plasma.
|
| Top Pathways |
Complement and coagulation cascades
|
