| Gene Symbol |
ATF6B
|
| Entrez Gene |
1388
|
| Alt Symbol |
CREB-RP, CREBL1, G13
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
activating transcription factor 6 beta
|
| Other Description |
Creb-related protein|cAMP response element-binding protein-related protein|cAMP responsive element binding protein-like 1|cAMP-dependent transcription factor ATF-6 beta|cAMP-responsive element-binding protein-like 1|cyclic AMP-dependent transcription factor ATF-6 beta|protein G13
|
| Swissprots |
Q13269 Q99635 Q9NPL0 Q14343 B0UYX6 Q9H3V9 Q9H3W1 Q99941 Q5SSW7 Q99637 Q14345
|
| Accessions |
AAB47487 AAG14898 AAG14900 CAA66663 CAB89295 EAX03581 EAX03582 EAX03583 EAX03584 EAX03585 Q99941 AK000928 BC008394 AAH08394 BC077075 AAH77075 BT007042 AAP35691 U31903 AAA97438 U52696 U52701 X98054 CAA66664 NM_001136153 NP_001129625 NM_004381 NP_004372
|
| Function |
Transcriptional factor that acts in the unfolded protein response (UPR) pathway by activating UPR target genes induced during ER stress. Binds DNA on the 5'-CCAC[GA]-3' half of the ER stress response element (ERSE) (5'-CCAATN(9)CCAC[GA]-3') when NF-Y is bound to ERSE.
|
| Subcellular Location |
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
|
| Tissue Specificity |
Ubiquitous.
|
| Top Pathways |
Estrogen signaling pathway, Thyroid hormone synthesis, cGMP-PKG signaling pathway, Dopaminergic synapse, Adrenergic signaling in cardiomyocytes
|