B3GAT3

Gene Symbol	B3GAT3
Entrez Gene	26229
Alt Symbol	GLCATI, glcUAT-I
Species	Human
Gene Type	protein-coding
Description	beta-1,3-glucuronyltransferase 3
Other Description	Sqv-8-like protein|UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase|beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)|galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3
Swissprots	B7ZAB3 Q9UEP0 Q96I06 O94766
Accessions	EAW74042 EAW74043 EAW74044 O94766 AB009598 BAA34537 AJ005865 CAA06742 AK075166 AK297970 BAG60280 AK310200 AK316228 BAH14599 BC007906 AAH07906 BC011173 BC019832 AAH19832 BC071961 AAH71961 HQ447823 ADQ32307 XM_011544936 XP_011543238 NM_001288721 NP_001275650 NM_001288722 NP_001275651 NM_001288723 NP_001275652 NM_012200 NP_036332 NR_109991
Function	Glycosaminoglycans biosynthesis. Involved in forming the linkage tetrasaccharide present in heparan sulfate and chondroitin sulfate. Transfers a glucuronic acid moiety from the uridine diphosphate-glucuronic acid (UDP-GlcUA) to the common linkage region trisaccharide Gal-beta-1,3-Gal-beta-1,4-Xyl covalently bound to a Ser residue at the glycosaminylglycan attachment site of proteoglycans. Can also play a role in the biosynthesis of l2/HNK-1 carbohydrate epitope on glycoproteins. Shows strict specificity for Gal-beta-1,3-Gal-beta-1,4-Xyl, exhibiting negligible incorporation into other galactoside substrates including Galbeta1-3Gal beta1-O-benzyl, Galbeta1-4GlcNAc and Galbeta1-4Glc. Stimulates 2-phosphoxylose phosphatase activity of PXYLP1 in presence of uridine diphosphate-glucuronic acid (UDP- GlcUA) during completion of linkage region formation. {ECO:0000269|PubMed:24425863}.
Subcellular Location	Golgi apparatus membrane {ECO:0000269|PubMed:21763480}; Single-pass type II membrane protein {ECO:0000269|PubMed:21763480}. Golgi apparatus, cis-Golgi network {ECO:0000269|PubMed:21763480}.
Tissue Specificity	Ubiquitous (but weakly expressed in all tissues examined).
Top Pathways	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate, Glycosaminoglycan biosynthesis - heparan sulfate / heparin

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human B3GAT3 full length protein - ab161932 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human B3GAT3 protein fragment - ab156962 from Abcam Category Protein Prices $297.00 Sizes 100 µg Source E. coli Species Human

Human B3GAT3 protein fragment - ab161933 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

B3GAT3 Antibody Blocking Peptide - LS-E1377 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

B3GAT3 Antibody Blocking Peptide - LS-E17049 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

beta-1,3-Glucuronyltransferase 3/B3GAT3 Recombinant Protein - H00026229-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

beta-1,3-Glucuronyltransferase 3/B3GAT3 Partial Recombinant Protein - H00026229-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human beta-1,3-Glucuronyltransferase 3/B3GAT3 Protein - NBP2-22712 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

B3GAT3-Antibody-C-term-Blocking-peptide - BP12032b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human B3GAT3, CF - 6808-GT-020 from R&D Systems Category Protein Source E. coli-derived, Glu72-Val335, with an N-terminal Met and 6-His tag

B3GAT3 (His Tag) protein - orb171530 from Biorbyt Category Protein Prices $298.00, $400.00 Sizes 10 μg, 20 μg Source E. coli Species Human

Human B3GAT3 protein - orb191419 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source Escherichia Coli. Species Human

B3GAT3 Blocking Peptide - 33R-7265 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

B3GAT3 protein (His tag) - 80R-2819 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

B3GAT3 (29-335, His-tag) - AR50938PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

B3GAT3 (29-335, His-tag) - AR50938PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

B3GAT3 - H00026229-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

B3GAT3 - H00026229-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

B3GAT3 - H00026229-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

B3GAT3 - H00026229-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

B3GAT3, 29-335aa, Human, His tag, E.coli - 01-P2114 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

B3GAT3 Recombinant Protein - 96-043 from ProSci Category Protein Prices $375.00 Sizes 100 µg Source E. coli Species Human

B3GAT3 fusion protein - ag9296 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

B3GAT3 fusion protein - Ag8362 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human B3GAT3, His-tagged - B3GAT3-7603H from Creative Biomart Category Protein Source E. coli Species Human

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