DAZL

Gene Symbol DAZL
Entrez Gene 1618
Alt Symbol DAZH, DAZL1, DAZLA, SPGYLA
Species Human
Gene Type protein-coding
Description deleted in azoospermia-like
Other Description DAZ homolog|DAZ-like autosomal|SPGY-like-autosomal|deleted in azoospermia-like 1|germline specific RNA binding protein|spermatogenesis gene on the Y-like autosomal
Swissprots O15396 Q5HYB4 Q92904 Q92909
Accessions AAB84361 ABK58591 CBH19255 EAW64278 EAW64279 Q92904 AK303026 BAG64152 AK310341 BC027595 AAH27595 BX648638 CAI45996 DB080081 DQ576044 EU176226 ABW03677 U65918 AAC50813 U66078 AAB63596 U66726 AAB39935 NM_001190811 NP_001177740 NM_001351 NP_001342
Function RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Predominantly cytoplasmic. Nuclear in spermatogonia until near the end of the meiotic prophase and cytoplasmic localization from then onward. {ECO:0000250}.
Tissue Specificity Testis specific. {ECO:0000269|PubMed:8896558, ECO:0000269|PubMed:8968755, ECO:0000269|PubMed:8968756}.

DAZL CRISPR/Cas9 KO Plasmid (h) - sc-418441 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAZL HDR Plasmid (h) - sc-418441-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAZL Double Nickase Plasmid (h) - sc-418441-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAZL Double Nickase Plasmid (h2) - sc-418441-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAZL CRISPR Activation Plasmid (h) - sc-418441-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAZL CRISPR Activation Plasmid (h2) - sc-418441-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAZL Lentiviral Activation Particles (h) - sc-418441-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAZL Lentiviral Activation Particles (h2) - sc-418441-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAZL siRNA (h) - sc-63280 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DAZL shRNA Plasmid (h) - sc-63280-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DAZL shRNA (h) Lentiviral Particles - sc-63280-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DAZL RNAi - H00001618-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU110731 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6941 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6941 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10460 from Sigma-Aldrich

Category miRNA

DAZL siRNA (Human) - CRH1140 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DAZL - MBS8232062 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human DAZL (NM_001351.3) - SHH274673 from Creative biogene

Category siRNA
Species Reactivities Human

Human DAZL siRNA - orb261642 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DAZL shRNA Plasmid (Human) - CHH1140 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DAZL miRNA 3'UTR clone - MiUTR3H-04148 from Creative biogene

Species Reactivities Human
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