| Gene Symbol | SPAST |
|---|---|
| Entrez Gene | 421481 |
| Alt Symbol | - |
| Species | Chicken |
| Gene Type | protein-coding |
| Description | spastin |
| Other Description | neuronal spastin |
| Swissprots | Q5ZK92 B5AH50 B5AH49 |
| Accessions | Q5ZK92 AJ720192 CAG31851 CR353646 EU849599 ACF60960 EU849600 ACF60961 NM_001031061 NP_001026232 |
| Function | ATP-dependent microtubule severing protein. Microtubule severing may promote reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Golgi and for completion of the abscission stage of cytokinesis. Also plays a role in axon growth and the formation of axonal branches. {ECO:0000255|HAMAP-Rule:MF_03021}. |
| Subcellular Location | Membrane {ECO:0000255|HAMAP-Rule:MF_03021}; Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_03021}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000255|HAMAP-Rule:MF_03021}. Cytoplasm, cytoskeleton {ECO:0000255|HAMAP-Rule:MF_03021}. Cytoplasm, perinuclear region {ECO:0000255|HAMAP-Rule:MF_03021}. Nucleus {ECO:0000255|HAMAP- Rule:MF_03021}. |
Recombinant Chicken SPAST - SPAST-2741C from Creative Biomart
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Spastin (SPAST), Recombinant Protein - MBS7057111 from MyBioSource
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Spastin (SPAST), Recombinant Protein - MBS7030250 from MyBioSource
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