GRIN1

Gene Symbol	GRIN1
Entrez Gene	2902
Alt Symbol	GluN1, MRD8, NMD-R1, NMDA1, NMDAR1, NR1
Species	Human
Gene Type	protein-coding
Description	glutamate receptor, ionotropic, N-methyl D-aspartate 1
Other Description	N-methyl-D-aspartate receptor channel, subunit zeta-1|N-methyl-D-aspartate receptor subunit NR1|glutamate [NMDA] receptor subunit zeta 1|glutamate [NMDA] receptor subunit zeta-1|glutamate receptor ionotropic, NMDA 1
Swissprots	Q5VSF6 Q5VSF3 A6NLK7 Q5VSF5 Q12868 Q9UPF9 Q05586 Q12867 Q5VSF4 A6NLR1 Q5VSF8 P35437 Q9UPF8 Q5VSF7 C9K0X1
Accessions	EAW88350 EAW88351 EAW88352 EAW88353 EAW88354 EAW88355 EAW88356 EAW88357 EAW88358 EAW88359 EAW88360 Q05586 AB208918 BAD92155 AB208999 BAD92236 AF015730 AAB67723 AF015731 AAB67724 BC156097 AAI56098 BC156961 AAI56962 BU728516 D13515 BAA02732 L05666 AAA21180 L13266 AAB59360 L13267 AAA36198 L13268 AAB59361 S57708 AAB25917 U08106 AAA62111 U08107 AAA62112 XM_005266071 XP_005266128 XM_005266072 XP_005266129 XM_005266073 XP_005266130 XM_011518583 XP_011516885 NM_000832 NP_000823 NM_001185090 NP_001172019 NM_001185091 NP_001172020 NM_007327 NP_015566 NM_021569 NP_067544
Function	NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. Note=Enriched in postsynaptic plasma membrane and postsynaptic densities. {ECO:0000250}.
Top Pathways	Amphetamine addiction, Circadian entrainment, Alcoholism, cAMP signaling pathway, Rap1 signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NMDAR1 protein fragment - ab158584 from Abcam Category Protein Source Wheat germ Species Human

NMDAR1 peptide - ab168728 from Abcam Category Peptide

NMDAR1(Phospho-Ser896) antibody blocking peptide - ab203399 from Abcam Category Peptide

Rat NMDAR1 peptide - ab17568 from Abcam Category Peptide Source CHO

GRIN1-Antibody-Center-K412-Blocking-peptide - BP19119c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GRIN1-Antibody-C-term-Blocking-peptide - BP5535b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NMDAR1 blocking peptide - GTX89302-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat

NMDAR1 Peptide - AC21-0968-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

NMDA Receptor 1 - H00002902-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NMDA Receptor 1 - H00002902-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

NMDA Receptor Peptide - 45-971P from ProSci Category Peptide Species Rat

NMDAR1 (Phospho-Ser896) Antibody Blocking Peptide - GWB-B82DA5 from Genway Biotech Category Peptide Prices $138.00 Sizes 100 µg

Recombinant Human GRIN1 - GRIN1-217H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 1 (GRIN1) - RPE805Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

NMDAR1 Blocking Peptide - CBP3977 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Dog

NMDAζ1 (S885) Peptide - BS1561P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

NMDAζ1 (F891) Peptide - BS3664P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

NMDAζ1 (F891) Peptide - BS3721P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

p-NMDAζ1 (S897) Peptide - BS4801P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

p-NMDAζ1 (S896) Peptide - BS5090P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

NMDAζ1 (S902) Peptide - BS5587P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

NMDAR1(Phospho-Ser896) antibody blocking peptide - 51104 from Signalway Antibody Category Peptide Prices $70.00 Sizes 100 µl

GRIN1 Peptide - abx164748 from Abbexa Category Peptide Species Human

NMDAR1 (pS896) Blocking Peptide - abx161872 from Abbexa Category Peptide Species Human, Mouse, Rat, Dog

NMDAR1 Blocking Peptide - abx161873 from Abbexa Category Peptide Species Human, Mouse, Rat, Dog

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