NPPB

Gene Symbol	NPPB
Entrez Gene	4879
Alt Symbol	BNP
Species	Human
Gene Type	protein-coding
Description	natriuretic peptide B
Other Description	brain type natriuretic peptide|gamma-brain natriuretic peptide|natriuretic peptide precursor B|natriuretic peptides B|natriuretic protein
Swissprots	Q9P2Q7 B0ZBE9 P16860 Q6FGY0
Accessions	AAA35603 ACA05917 BAA04067 BAA90441 BAD06457 BAF64842 EAW71718 EAW71719 P16860 AJ708502 BC025785 AAH25785 CR541976 CAG46774 CR542003 CAG46800 M25296 AAA36355 NM_002521 NP_002512
Function	Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3. {ECO:0000269|PubMed:1672777}.
Subcellular Location	Secreted.
Tissue Specificity	Brain and also in atria, but at much lower levels than ANP.
Top Pathways	cGMP-PKG signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

BNP Human ELISA Kit - ab193694 from Abcam Category ELISA Kit Prices $475.00 Sizes 1 x 96 tests Sensitivity 14 pg/ml Range 14 pg/ml - 1000 pg/ml

proBNP Human ELISA Kit - ab193712 from Abcam Category ELISA Kit Prices $475.00 Sizes 1 x 96 tests Sensitivity 0.14 ng/ml Range 0.14 ng/ml - 100 ng/ml

Human NPPB / BNP ELISA Kit - LS-F5579 from LifeSpan Bioscience Category ELISA Kit Prices $580.00 Sizes 1 plate Sensitivity 12.6 pg/ml Range 31.25 - 2000 pg/ml

Rat NPPB / BNP ELISA Kit (Competitive EIA) - LS-F5581 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 8.65 pg/ml Range 31.25-2000 pg/ml

Mouse NPPB / BNP EIA Kit - LS-F5580 from LifeSpan Bioscience Category ELISA Kit Prices $670.00 Sizes 1 plate Sensitivity 4.68 pg/ml Range 12.35 - 1000 pg/ml

Pig NPPB / BNP ELISA Kit (Sandwich ELISA) - LS-F5336 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 31.25 pg/ml Range 31.25-2000 pg/ml

Dog NPPB / BNP ELISA Kit - LS-F5843 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 11.9 pg/ml Range 31.25 - 2000 pg/ml

Dog NPPB / BNP ELISA Kit (Competitive EIA) - LS-F9782 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 8.86 pg/ml Range 31.25-2000 pg/ml

Human NPPB / BNP ELISA Kit (Competitive EIA) - LS-F9798 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 9.24 pg/ml Range 31.25-2000 pg/ml

Mouse NPPB / BNP ELISA Kit (Competitive EIA) - LS-F10816 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 15.6 Range 31.25-2000 pg/ml

Rat NPPB / BNP ELISA Kit (Sandwich ELISA) - LS-F10814 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 31.2 pg/ml Range 31.25-2000 pg/ml

Dog NPPB / BNP ELISA Kit (Sandwich ELISA) - LS-F10815 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.156 Range 31.25-2000 pg/ml

Human NPPB / Natriuretic Peptides B ELISA Kit - RAB0630 from Sigma-Aldrich Category ELISA Kit Prices $637.00 Sizes 1 kt

Human proNPPB / Natriuretic Peptides B ELISA Kit - RAB0726 from Sigma-Aldrich Category ELISA Kit Prices $637.00 Sizes 1 kt

Brain Natriuretic Peptide EIA Kit - RAB0386 from Sigma-Aldrich Prices $399.50 Sizes 1 kt

Human BNP ELISA Kit - abx150828 from Abbexa Category ELISA Kit Sensitivity 12.6 pg/ml Range 31.25 pg/ml - 2000 pg/ml

Human BNP ELISA Kit - abx150829 from Abbexa Category ELISA Kit Sensitivity 8.47 pg/ml Range 24.69 pg/ml - 2000 pg/ml

Brain Natriuretic Peptide, BNP, Human, ELISA Kit - E-EL-H0598 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 18.75 Range 31.25-2000pg/mL

Natriuretic peptides B (NPPB), Human, ELISA Kit - E01N0556 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Natriuretic peptides B, NPPB, Human, ELISA Kit - E0541h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 15.6-1000 pg/mL

Brain Natriuretic Peptide, BNP, Mouse, ELISA Kit - E-EL-M0204 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 9.375 Range 15.625-1000pg/mL

Brain Natriuretic Peptide, BNP, Rat, ELISA Kit - E-EL-R0126 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 18.75 Range 31.25-2000pg/mL

Brain Natriuretic Peptide, BNP, Rabbit, ELISA Kit - E-EL-RB0258 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 18.75 Range 31.25-2000pg/mL

Brain Natriuretic Peptide, BNP, Chicken, ELISA Kit - E-EL-Ch0927 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Brain Natriuretic Peptide, BNP, Porcine, ELISA Kit - E-EL-P0023 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 18.75 Range 31.25-2000pg/mL

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