Gene Symbol | ADAM23 |
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Entrez Gene | 8745 |
Alt Symbol | MDC-3, MDC3 |
Species | Human |
Gene Type | protein-coding |
Description | ADAM metallopeptidase domain 23 |
Other Description | disintegrin and metalloproteinase domain-containing protein 23|metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3 |
Swissprots | A2RU59 O75077 |
Accessions | AAD55252 AAX93195 AAX93210 AAY14948 CAI93690 EAW70386 EAW70387 O75077 AB009672 BAA32351 AF052115 AJ005580 CAC20565 AK091800 AK129906 AK296844 BAG59410 BC132763 AAI32764 BC132765 AAI32766 CN399765 H11006 R43984 XM_005246932 XP_005246989 XM_011512086 XP_011510388 NM_003812 NP_003803 |
Function | May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein. |
Subcellular Location | Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Tissue Specificity | Highly expressed in the brain and weakly expressed in the heart. In the brain, expressed prominently in the amygdala, caudate nucleus, hypothalamus, thalamus, cerebral cortex and occipital pole. {ECO:0000269|PubMed:14697522}. |
ADAM23 CRISPR/Cas9 KO Plasmid (h) - sc-403703 from Santa Cruz Biotechnology
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ADAM23 HDR Plasmid (h) - sc-403703-HDR from Santa Cruz Biotechnology
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ADAM23 Double Nickase Plasmid (h) - sc-403703-NIC from Santa Cruz Biotechnology
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ADAM23 Double Nickase Plasmid (h2) - sc-403703-NIC-2 from Santa Cruz Biotechnology
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ADAM23 CRISPR Activation Plasmid (h) - sc-403703-ACT from Santa Cruz Biotechnology
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ADAM23 CRISPR Activation Plasmid (h2) - sc-403703-ACT-2 from Santa Cruz Biotechnology
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ADAM23 Lentiviral Activation Particles (h) - sc-403703-LAC from Santa Cruz Biotechnology
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ADAM23 Lentiviral Activation Particles (h2) - sc-403703-LAC-2 from Santa Cruz Biotechnology
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ADAM23 siRNA (h) - sc-61938 from Santa Cruz Biotechnology
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ADAM23 shRNA Plasmid (h) - sc-61938-SH from Santa Cruz Biotechnology
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ADAM23 shRNA (h) Lentiviral Particles - sc-61938-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU015091 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2814 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2814 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02787 from Sigma-Aldrich
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ADAM23 siRNA (Human) - CRH5763 from Cohesion Biosciences
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ADAM23 - MBS8235404 from MyBioSource
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shRNA set against Human ADAM23 (NM_003812.2) - SHH231522 from Creative biogene
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shRNA set against Human ADAM23(NM_003812.2) - SHG038401 from Creative biogene
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Human ADAM23 siRNA - orb266265 from Biorbyt
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ADAM23 shRNA Plasmid (Human) - CHH5763 from Cohesion Biosciences
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ADAM23 miRNA 3'UTR clone - MiUTR1H-00159 from Creative biogene
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