| Gene Symbol |
CTSA
|
| Entrez Gene |
5476
|
| Alt Symbol |
GLB2, GSL, NGBE, PPCA, PPGB
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cathepsin A
|
| Other Description |
beta-galactosidase 2|beta-galactosidase protective protein|carboxypeptidase C|carboxypeptidase L|carboxypeptidase Y-like kininase|carboxypeptidase-L|deamidase|lysosomal carboxypeptidase A|lysosomal protective protein|protective protein cathepsin A|urinary kininase
|
| Swissprots |
Q561W6 Q5JZH1 Q9BW68 B2R798 P10619 Q9BR08 Q96KJ2
|
| Accessions |
AAM09560 CCQ43096 EAW75788 EAW75789 P10619 AB209705 BAD92942 AF086236 AK055177 AK097786 AK172808 AK304536 BAG65336 AK307701 AK312898 BAG35745 BC000597 AAH00597 BC093009 AAH93009 DA029446 DQ891935 ABM82861 DQ895122 ABM86048 M22960 AAA36476 NM_000308 NP_000299 NM_001127695 NP_001121167 NM_001167594 NP_001161066
|
| Function |
Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins. {ECO:0000269|PubMed:1907282}.
|
| Subcellular Location |
Lysosome.
|
| Top Pathways |
Lysosome, Renin-angiotensin system
|
![Western Blot: Cathepsin A Overexpression Lysate (Adult Normal) [NBL1-09586] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Cathepsin A.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2686_Cathepsin%2520A%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-09586-img0002.jpg)