ZBTB7A

Gene Symbol	ZBTB7A
Entrez Gene	51341
Alt Symbol	FBI-1, FBI1, LRF, ZBTB7, ZNF857A, pokemon
Species	Human
Gene Type	protein-coding
Description	zinc finger and BTB domain containing 7A
Other Description	HIV-1 1st-binding protein 1|HIV-1 inducer of short transcripts binding protein|POK erythroid myeloid ontogenic factor|POZ and Krueppel erythroid myeloid ontogenic factor|TIP21|TTF-I-interacting peptide 21|factor binding IST protein 1|factor that binds to inducer of short transcripts protein 1|leukemia/lymphoma-related factor|lymphoma related factor|zinc finger and BTB domain containing 7A, HIV-1 inducer of short transcripts binding protein|zinc finger and BTB domain-containing protein 7A|zinc finger protein 857A
Swissprots	Q5XG86 O00456 O95365 Q14D41 D6W619
Accessions	EAW69266 EAW69267 EAW69268 EAW69269 EAW69270 EAW69271 EAW69272 O95365 AF000561 AAB58414 AF097916 AAC72973 AL390151 BC019108 AAH19108 BC080608 BC084568 AAH84568 BC113511 AAI13512 BM696365 BQ082585 BQ711712 CB047382 CB242327 XM_005259570 XP_005259627 XM_005259571 XP_005259628 XM_005259572 XP_005259629 NM_015898 NP_056982
Function	Plays a key role in the instruction of early lymphoid progenitors to develop into B lineage by repressing T-cell instructive Notch signals (By similarity). Specifically represses the transcription of the CDKN2A gene. Efficiently abrogates E2F1- dependent CDKN2A transactivation/de-repression. Binds to the consensus sequence 5'-[GA][CA]GACCCCCCCCC-3' (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000250}.
Tissue Specificity	Widely expressed. In normal thymus, expressed in medullary epithelial cells and Hassle's corpuscles (at protein level). In tonsil, expressed in squamous epithelium and germinal center lymphocytes (at protein level). Up-regulated in a subset of lymphomas, as well as in a subset of breast, lung, colon, prostate and bladder carcinomas (at protein level). {ECO:0000269|PubMed:15662416, ECO:0000269|PubMed:9927193}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SignalSilence ® LRF/Pokemon siRNA I - 13350 from Cell Signaling Technology Category siRNA Prices $256.00 Sizes 300 µl (3 nmol) Species Reactivities Human

LRF CRISPR/Cas9 KO Plasmid (h) - sc-402016 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

LRF HDR Plasmid (h) - sc-402016-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

LRF Double Nickase Plasmid (h) - sc-402016-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

LRF Double Nickase Plasmid (h2) - sc-402016-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

LRF CRISPR Activation Plasmid (h) - sc-402016-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

LRF CRISPR Activation Plasmid (h2) - sc-402016-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

LRF Lentiviral Activation Particles (h) - sc-402016-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

LRF Lentiviral Activation Particles (h2) - sc-402016-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

LRF siRNA (h) - sc-44574 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

LRF shRNA Plasmid (h) - sc-44574-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

LRF shRNA (h) Lentiviral Particles - sc-44574-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN23085 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23085 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

ZBTB7A siRNA (Human) - CRH9713 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ZBTB7A/Pokemon RNAi - H00051341-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

ZBTB7A - MBS8204291 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human ZBTB7A (NM_015898.2) - SHH449268 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human ZBTB7A(NM_015898.2) - SHL142570 from Creative biogene Category siRNA Species Reactivities Human

ZBTB7A shRNA Plasmid (Human) - CHH9713 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

ZBTB7A miRNA 3'UTR clone - MiUTR1H-11385 from Creative biogene Species Reactivities Human

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