| Gene Symbol |
PLA2G4A
|
| Entrez Gene |
100008748
|
| Alt Symbol |
CPLA2, PLA2G4
|
| Species |
Rabbit
|
| Gene Type |
protein-coding
|
| Description |
phospholipase A2, group IVA (cytosolic, calcium-dependent)
|
| Other Description |
Phospholipase A2 group IVA|cytosolic phospholipase A2|phosphatidyl choline 2-acylhydrolase cPLA2
|
| Swissprots |
Q9TT38
|
| Accessions |
Q9TT38 AF204923 AAF15299 GBCH01157080 XM_008268662 XP_008266884 XM_008268663 XP_008266885 XM_008268664 XP_008266886 NM_001082072 NP_001075541
|
| Function |
Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Note=Translocates to membrane vesicles in a calcium-dependent fashion. {ECO:0000250}.
|
| Top Pathways |
Choline metabolism in cancer, Oxytocin signaling pathway, Inflammatory mediator regulation of TRP channels, Ovarian steroidogenesis, Glutamatergic synapse
|