PLA2G4A

Gene Symbol PLA2G4A
Entrez Gene 100008748
Alt Symbol CPLA2, PLA2G4
Species Rabbit
Gene Type protein-coding
Description phospholipase A2, group IVA (cytosolic, calcium-dependent)
Other Description Phospholipase A2 group IVA|cytosolic phospholipase A2|phosphatidyl choline 2-acylhydrolase cPLA2
Swissprots Q9TT38
Accessions Q9TT38 AF204923 AAF15299 GBCH01157080 XM_008268662 XP_008266884 XM_008268663 XP_008266885 XM_008268664 XP_008266886 NM_001082072 NP_001075541
Function Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Note=Translocates to membrane vesicles in a calcium-dependent fashion. {ECO:0000250}.
Top Pathways Choline metabolism in cancer, Oxytocin signaling pathway, Inflammatory mediator regulation of TRP channels, Ovarian steroidogenesis, Glutamatergic synapse