Gene Symbol |
Rce1
|
Entrez Gene |
309153
|
Alt Symbol |
-
|
Species |
Rat
|
Gene Type |
protein-coding
|
Description |
Ras converting CAAX endopeptidase 1
|
Other Description |
CAAX prenyl protease 2|FACE-2|RCE1 homolog, prenyl protein peptidase|RCE1 homolog, prenyl protein protease|farnesylated proteins-converting enzyme 2|prenyl protein-specific endoprotease 2
|
Swissprots |
B0BMW8
|
Accessions |
B0BMW8 EDM12412 EDM12413 BC087629 AAH87629 BC158593 AAI58594 XM_006230788 XP_006230850 XM_006230790 XP_006230852 XM_006230791 XP_006230853 XM_008760135 XP_008758357 XM_008760136 XP_008758358 NM_001100585 NP_001094055
|
Function |
Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins. Seems to be able to process K-Ras, N-Ras, H-Ras, RAP1B and G-gamma-1 (By similarity). {ECO:0000250}.
|
Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
Top Pathways |
Terpenoid backbone biosynthesis
|