Gene Symbol |
Psmb9
|
Entrez Gene |
16912
|
Alt Symbol |
Lmp-2, Lmp2
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
|
Other Description |
LMP-2d|large multifunctional protease 2|low molecular mass protein 2|macropain chain 7|multicatalytic endopeptidase complex chain 7|proteasome chain 7|proteasome subunit beta type-9|proteasome subunit beta-1i|proteosome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)|proteosome beta 9 subunit|really interesting new gene 12 protein
|
Swissprots |
P28076 O09085 Q64278 Q07704 O09151 Q60827 O35522
|
Accessions |
AAA39439 AAA98932 AAB81528 AAC69911 BAA19855 BAA40680 EDL10257 EDL10258 O35522 P28076 AK008429 BAB25664 AK152743 BAE31463 AK171670 BAE42601 BC032210 BC116364 AAI16365 CT010227 CAJ18435 D44454 BAA22575 D44456 BAA22577 D44457 BAA22578 D44458 BAA22579 D44461 BAA22582 KJ650226 AIC84014 S58203 AAP13903 S59862 AAB20105 U22447 AAA75304 U22448 AAA75305 U22919 AAA75306 U22920 AAA75307 XM_006523730 XP_006523793 XM_006525330 XP_006525393 XM_006536548 XP_006536611 XM_006537282 XP_006537345 NM_013585 NP_038613
|
Function |
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.
|
Subcellular Location |
Cytoplasm {ECO:0000255|PROSITE- ProRule:PRU00809}. Nucleus {ECO:0000250}.
|
Top Pathways |
Proteasome
|