| Gene Symbol |
FOS
|
| Entrez Gene |
396512
|
| Alt Symbol |
-
|
| Species |
Chicken
|
| Gene Type |
protein-coding
|
| Description |
FBJ murine osteosarcoma viral oncogene homolog
|
| Other Description |
c-fos proto-oncogene|cellular oncogene fos|proto-oncogene c-Fos|proto-oncogene protein c-fos|v-fos FBJ murine osteosarcoma viral oncogene homolog
|
| Swissprots |
P11939
|
| Accessions |
AAA76823 P11939 M37000 AAA48670 Y00659 NM_205508 NP_990839
|
| Function |
Nuclear phosphoprotein which forms a tight but non- covalently linked complex with the JUN/AP-1 transcription factor. FOS has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, may activate phospholipid synthesis (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus. Endoplasmic reticulum {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}. Note=In quiescent cells, may be present in very small amounts in the cytosol. Following induction of cell growth, first localizes to the endoplasmic reticulum and later to the nucleus (By similarity). {ECO:0000250}.
|
| Top Pathways |
Toll-like receptor signaling pathway, MAPK signaling pathway, Salmonella infection, Herpes simplex infection
|