| Gene Symbol |
Ugt1a2
|
| Entrez Gene |
22236
|
| Alt Symbol |
UDPGT 1-2, Ugt1
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
UDP glucuronosyltransferase 1 family, polypeptide A2
|
| Other Description |
UDP-glucuronosyltransferase 1 family, member 2|UDP-glucuronosyltransferase 1 family, polypeptide A2|UDP-glucuronosyltransferase 1-2|UDP-glucuronosyltransferase 1A2|UDPGT|UGT1*0|UGT1-02|UGT1.2|bilirubin specific|bilirubin-specific UDPGT
|
| Swissprots |
P70691 Q545X2 Q6XL49
|
| Accessions |
EDL40122 P70691 AK002629 BAB22243 AY227195 AAP48594 BC138676 AAI38677 BC145969 AAI45970 D87866 BAA13482 NM_013701 NP_038729
|
| Function |
UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.
|
| Subcellular Location |
Microsome {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Expressed in kidney. {ECO:0000269|PubMed:14672974}.
|
| Top Pathways |
Chemical carcinogenesis, Steroid hormone biosynthesis, Drug metabolism - other enzymes, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450
|