Ugt1a2

Gene Symbol Ugt1a2
Entrez Gene 22236
Alt Symbol UDPGT 1-2, Ugt1
Species Mouse
Gene Type protein-coding
Description UDP glucuronosyltransferase 1 family, polypeptide A2
Other Description UDP-glucuronosyltransferase 1 family, member 2|UDP-glucuronosyltransferase 1 family, polypeptide A2|UDP-glucuronosyltransferase 1-2|UDP-glucuronosyltransferase 1A2|UDPGT|UGT1*0|UGT1-02|UGT1.2|bilirubin specific|bilirubin-specific UDPGT
Swissprots P70691 Q545X2 Q6XL49
Accessions EDL40122 P70691 AK002629 BAB22243 AY227195 AAP48594 BC138676 AAI38677 BC145969 AAI45970 D87866 BAA13482 NM_013701 NP_038729
Function UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.
Subcellular Location Microsome {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Tissue Specificity Expressed in kidney. {ECO:0000269|PubMed:14672974}.
Top Pathways Chemical carcinogenesis, Steroid hormone biosynthesis, Drug metabolism - other enzymes, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450