MMP2

Gene Symbol	MMP2
Entrez Gene	4313
Alt Symbol	CLG4, CLG4A, MMP-2, MMP-II, MONA, TBE-1
Species	Human
Gene Type	protein-coding
Description	matrix metallopeptidase 2
Other Description	72 kDa type IV collagenase|collagenase type IV-A|matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)|matrix metalloproteinase-2|matrix metalloproteinase-II|neutrophil gelatinase
Swissprots	E9PE45 B4DWH3 B2R6U1 P08253 Q9UCJ8
Accessions	AAA52027 AAA52028 AAU10089 CAR95108 CAS92766 EAW82824 EAW82825 EAW82826 EAW82827 EAW82828 P08253 AK301536 BAG63035 AK310314 AK312711 BAG35588 AL046162 AL542407 AL832088 AU133104 AU279927 BC002576 AAH02576 BP341649 BQ004983 BX357054 CA446916 DA579926 DA739456 DA993141 DB059054 DB154582 DQ385623 ABD38929 DQ891952 ABM82878 DQ895138 ABM86064 J03210 AAA35701 X58968 NM_001127891 NP_001121363 NM_001302508 NP_001289437 NM_001302509 NP_001289438 NM_001302510 NP_001289439 NM_004530 NP_004521
Function	Isoform 2: Mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro- inflammatory NF-kappaB, NFAT and IRF transcriptional pathways.
Subcellular Location	Isoform 1: Secreted, extracellular space, extracellular matrix. Membrane. Nucleus. Note=Colocalizes with integrin alphaV/beta3 at the membrane surface in angiogenic blood vessels and melanomas. Found in mitochondria, along microfibrils, and in nuclei of cardiomyocytes.
Tissue Specificity	Produced by normal skin fibroblasts. PEX is expressed in a number of tumors including gliomas, breast and prostate. {ECO:0000269|PubMed:11751392}.
Top Pathways	Leukocyte transendothelial migration, Bladder cancer, GnRH signaling pathway, Estrogen signaling pathway, Proteoglycans in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MMP2 Human ELISA kit - ab100606 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity < 3.5 ng/ml Range 3.3 ng/ml - 800 ng/ml

Rat MMP2 ELISA Kit (Sandwich ELISA) - LS-F5517 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.128 ng/ml Range 625-40000 pg/ml

Rat MMP2 ELISA Kit (Sandwich ELISA) - LS-F2602 from LifeSpan Bioscience Category ELISA Kit Prices $570.00 Sizes 1 plate Sensitivity 10 pg/ml Range 625-40000 pg/ml

Mouse MMP2 ELISA Kit (Sandwich ELISA) - LS-F2513 from LifeSpan Bioscience Category ELISA Kit Prices $570.00 Sizes 1 plate Sensitivity 625 pg/ml Range 625-40000 pg/ml

Human MMP2 ELISA Kit (Sandwich ELISA) - LS-F2512 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Sensitivity 625 pg/ml Range 625-40000 pg/ml

Rabbit MMP2 ELISA Kit (Sandwich ELISA) - LS-F4637 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 1.35 pg/ml Range 625-40000 pg/ml

Human MMP2 ELISA Kit (Sandwich ELISA) - LS-F4963 from LifeSpan Bioscience Category ELISA Kit Prices $440.00 Sizes 1 plate Sensitivity 13.1 pg/ml Range 625-40000 pg/ml

Mouse MMP2 ELISA Kit (Sandwich ELISA) - LS-F4964 from LifeSpan Bioscience Category ELISA Kit Prices $670.00 Sizes 1 plate Sensitivity 0.063 ng/ml Range 625-40000 pg/ml

Human MMP2 ELISA Kit (Sandwich ELISA) - LS-F157 from LifeSpan Bioscience Category ELISA Kit Prices $460.00, $840.00, $1,960.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 3.277 ng/ml Range 625-40000 pg/ml

Mouse MMP2 ELISA Kit (Sandwich ELISA) - LS-F276 from LifeSpan Bioscience Category ELISA Kit Prices $460.00, $840.00, $1,960.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 27.43 pg/ml Range 625-40000 pg/ml

Mouse/Human/Rat MMP2 ELISA Kit (Cell-Based ELISA) - LS-F2161 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 625-40000 pg/ml

Pig MMP2 ELISA Kit (Sandwich ELISA) - LS-F7320 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 31.2 pg/ml Range 625-40000 pg/ml

Horse MMP2 ELISA Kit (Sandwich ELISA) - LS-F9851 from LifeSpan Bioscience Category ELISA Kit Prices $790.00 Sizes 1 plate Sensitivity 0.59 ng/ml Range 625-40000 pg/ml

Rabbit MMP2 ELISA Kit - LS-F12062 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.78 Range 0.78 - 50 ng/ml

Human MMP-2 ELISA Kit - RAB0365 from Sigma-Aldrich Category ELISA Kit Prices $423.50 Sizes 1 kt

Human MMP-2 Luminex Performance Assay - LMP902C from R&D Systems

Human MMP-2 Magnetic Luminex Performance Assay - LMPM902 from R&D Systems

Human MMP-2 DuoSet ELISA - DY902 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 0.63 - 20 ng/mL

Human MMP-2/TIMP-2 Complex DuoSet ELISA - DY1497 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 125.00 - 8,000 pg/mL

Human MMP-2/TIMP-4 Complex DuoSet ELISA - DY1498 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 125.00 - 8,000 pg/mL

Human MMP-2/TIMP-1 Complex DuoSet ELISA - DY1496 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 156.00 - 10,000 pg/mL

Quantikine Immunoassay Control Set 923 for Total MMP-2 - QC126 from R&D Systems Category ELISA Kit Prices $125.00 Sizes 1 each

Total MMP-2 Quantikine SixPak (6 Plates)For human, mouse, rat, porcine, and canine samples. - SMMP200 from R&D Systems Category ELISA Kit Sensitivity 0.082 ng/mL Range 0.5 - 32 ng/mL (Serum, Heparin Plasma, Cell Culture Supernates, EDTA Plasma)

Total MMP-2 Quantikine PharmPak (50 Plates)For human, mouse, rat, porcine, and canine samples. - PMMP200 from R&D Systems Category ELISA Kit Sensitivity 0.082 ng/mL Range 0.5 - 32 ng/mL (Serum, Heparin Plasma, Cell Culture Supernates, EDTA Plasma)

Total MMP-2 Quantikine ELISA Kit - MMP200 from R&D Systems Category ELISA Kit Prices $479.00, $2,290.00, $14,070.00 Sizes 1 kit, 1 pack (6 Plates), 1 pack (50 Plates) Sensitivity 0.082 ng/mL Range 0.5 - 32 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma)

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