PTK2

Gene Symbol PTK2
Entrez Gene 396416
Alt Symbol FAK, FRNK, p125FAK
Species Chicken
Gene Type protein-coding
Description protein tyrosine kinase 2
Other Description FADK 1|PTK2 protein tyrosine kinase 2|focal adhesion kinase 1|focal adhesion kinase-related nonkinase|p41/p43FRNK|pp125FAK|protein-tyrosine kinase 2
Swissprots Q00944
Accessions Q00944 L07415 AAA48773 L08402 AAA48766 M86656 AAA48765 NM_205435 NP_990766
Function Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development, embryonic angiogenesis, normal cardiomyocyte migration and proliferation, and normal heart development. Regulates axon growth and neuronal cell migration, axon branching and synapse formation; required for normal development of the nervous system. Plays a role in osteogenesis and differentiation of osteoblasts. Functions in integrin signal transduction, but also in signaling downstream of numerous growth factor receptors, G-protein coupled receptors (GPCR), ephrin receptors, netrin receptors and LDL receptors. Forms multisubunit signaling complexes with SRC and SRC family members upon activation; this leads to the phosphorylation of additional tyrosine residues, cre
Subcellular Location Cell junction, focal adhesion {ECO:0000269|PubMed:8423801}. Cell membrane {ECO:0000269|PubMed:8423801}; Peripheral membrane protein {ECO:0000269|PubMed:8423801}; Cytoplasmic side {ECO:0000269|PubMed:8423801}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:8423801}. Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Nucleus {ECO:0000269|PubMed:8423801}. Note=Constituent of focal adhesions. Detected at microtubules (By similarity). {ECO:0000250}.
Top Pathways VEGF signaling pathway, Focal adhesion, ErbB signaling pathway, Regulation of actin cytoskeleton

Chicken PTK2 protein - orb245594 from Biorbyt

Category Protein
Prices $340.00, $629.00, $1,003.00, $1,556.00
Sizes 50 μg, 200 μg, 500 μg, 1 mg
Species Chicken

Recombinant Chicken PTK2 - PTK2-6985C from Creative Biomart

Category Protein
Source Mammalian Cells
Species Chicken

recombinant chicken Focal adhesion kinase 1 - CSB-EP144494h CSB-BP144494h CSB-MP144494h from Cusabio

Category Protein
Source E.coli or Baculovirus or Mammalian cell
Species Chicken

recombinant human Focal adhesion kinase 1 - CSB-RP144494h from Cusabio

Category Protein
Source E.coli
Species Human

Recombinant Chicken Focal adhesion kinase 1(PTK2) ,partial - CSB-YP018993CH CSB-EP018993CH CSB-BP018993CH CSB-MP018993CH from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Chicken

Focal adhesion kinase 1, Recombinant Protein - MBS1265406 from MyBioSource

Category Protein
Prices $190.00, $460.00, $750.00, $1,180.00
Sizes 50 µg (E-Coli), 200 µg (E-Coli), 500 µg (E-Coli), 1 mg (E-Coli)
Source E Coli

Focal adhesion kinase 1 (PTK2), partial, Recombinant Protein - MBS952569 from MyBioSource

Category Protein
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Chicken

Chicken PTK2 protein - orb54092 from Biorbyt

Category Protein
Prices $213.00, $408.00, $612.00, $680.00, $1,122.00, $1,777.00
Sizes 10 μg, 50 μg, 100 μg, 200 μg, 500 μg, 1 mg
Species Chicken

Recombinant Chicken Focal adhesion kinase 1(PTK2),partial - CSB-RP144494CH from Cusabio

Category Protein
Source E.coli
Species Chicken

recombinant chicken Focal adhesion kinase 1 - AP72254 from Signalway Antibody

Category Protein
Prices $260.00, $735.00, $1,240.00, $1,975.00
Sizes 50 µg, 200 µg, 500 µg, 1 mg
Source E.coli
Species Chicken

Focal adhesion kinase 1, Recombinant Protein - MBS9422006 from MyBioSource

Category Protein
Prices $280.00, $665.00, $1,080.00, $1,690.00
Sizes 50 µg, 200 µg, 500 µg, 1 mg
Source E Coli
Species Chicken

PTK2 Recombinant Protein (Chicken) (OPCA04053) - OPCA04053 from Aviva Systems Biology

Category Protein
Species Chicken

Recombinant Chicken PTK2 Protein (376-683 aa), GST-tagged - PTK2-1272C from Creative Biomart

Category Protein
Source E. coli
Species Chicken
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