PF4

Gene Symbol	PF4
Entrez Gene	5196
Alt Symbol	CXCL4, PF-4, SCYB4
Species	Human
Gene Type	protein-coding
Description	platelet factor 4
Other Description	C-X-C motif chemokine 4|chemokine (C-X-C motif) ligand 4|iroplact|oncostatin-A
Swissprots	Q9UC65 Q53X61 Q9UC64 P02776
Accessions	AAK29643 AAY41003 EAX05694 P02776 AJ705588 BC093965 AAH93965 BC112093 AAI12094 CR407677 CAG28605 GD143506 M25897 AAA60066 XM_005265696 XP_005265753 NM_002619 NP_002610
Function	Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form. {ECO:0000269|PubMed:7644496}.
Subcellular Location	Secreted.
Top Pathways	Cytokine-cytokine receptor interaction, Chemokine signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

Active human PF4 full length protein - ab9562 from Abcam Category Protein Prices $110.00, $239.00 Sizes 5 µg, 20 µg Source E. coli Species Human

Active human PF4 full length protein - ab191770 from Abcam Category Protein Prices $192.00 Sizes 20 µg Source E. coli Species Human

Active human PF4 full length protein - ab80477 from Abcam Category Protein Prices $450.00 Sizes 100 µg Source Native Species Human

Human PF4 full length protein - ab156343 from Abcam Category Protein Source E. coli Species Human

Human PF4 full length protein - ab81754 from Abcam Category Protein Source Native Species Human

Human PF4 peptide - ab96111 from Abcam Category Peptide

CXCL4/PF4 Recombinant Protein - H00005196-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

CXCL4/PF4 Partial Recombinant Protein - H00005196-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

CXCL4/PF4 Protein - NBP2-23336 from Novus Biologicals Category Protein Prices $309.00 Sizes 20 µg Species Human

CXCL4/PF4 Protein - P4061 from Novus Biologicals Category Protein Prices $549.00 Sizes 20 µg Species Human

CXCL4/PF4 Native Protein - NBP1-99426 from Novus Biologicals Category Protein Prices $190.00 Sizes 20 µg Source Human platelets Species Human

CXCL4/PF4 Native Protein - NBP2-12560 from Novus Biologicals Category Protein Prices $465.00 Sizes 100 µg Source Human Species Human

PF4 Recombinant Protein (Active) - GTX48162-PRO from GeneTex Category Protein Prices $299.00 Sizes 20 μg Source E. coli Species Human

Recombinant Human CXCL4/PF4 - 795-P4-025 from R&D Systems Category Protein Source E. coli-derived, Glu32-Ser101

Recombinant Human CXCL4/PF4, CF - 795-P4-025/CF from R&D Systems Category Protein Source E. coli-derived, Glu32-Ser101

Recombinant Human CXCL4/PF4 (Mammalian-expressed), CF - 7989-P4-025/CF from R&D Systems Category Protein Source Human embryonic kidney cell, HEK293-derived, Glu32-Ser101

Human Platelet Factor 4 Protein (OPMA04374) - OPMA04374 from Aviva Systems Biology Category Protein Prices $365.00 Sizes 100 µg Source Supernatant of thrombin-activated platelets (human) Species Human

PF 4 Protein (OPPA01495) - OPPA01495 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source Human Platelets

PF 4 Protein (OPPA01598) - OPPA01598 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Recombinant Human Platelet Factor-4 (CXCL4) Variant-1 Protein (OPPA02067) - OPPA02067 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 1 µg Species Human

Human Platelet Factor 4 protein - orb82294 from Biorbyt Category Protein Prices $485.00 Sizes 100 μg Source Sample obtained from Human. Species Human

Murine PF-4 protein - orb107796 from Biorbyt Category Protein Prices $221.00, $357.00, $553.00, $910.00 Sizes 5 μg, 20 μg, 100 μg, 250 μg Source E.coli

Human Platelet Factor-4 protein - orb80688 from Biorbyt Category Protein Prices $230.00, $442.00 Sizes 5 μg, 20 μg Source Human Platelets Species Human

Human PF 4 protein - orb80689 from Biorbyt Category Protein Prices $187.00, $323.00, $3,128.00 Sizes 5 μg, 20 μg, 1 mg Species Human

Human PF4 , His protein - orb191336 from Biorbyt Category Protein Prices $170.00, $289.00, $1,139.00 Sizes 2 μg, 10 μg, 100 μg Source E. coli Species Human

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