Postn
| Gene Symbol | Postn |
|---|---|
| Entrez Gene | 50706 |
| Alt Symbol | A630052E07Rik, AI747096, OSF-2, Osf2, PLF, PN, peri |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | periostin, osteoblast specific factor |
| Other Description | osteoblast specific factor 2 (fasciclin I-like)|osteoblast-specific factor 2|periostin|periostin-like factor |
| Swissprots | Q8BMJ6 Q8K1K0 Q62009 |
| Accessions | EDL35257 EDL35258 EDL35259 EDL35260 EDL35261 Q62009 AK030756 BAC27122 AK042015 AK052220 AK154049 BAE32339 AK163070 AY651928 AAT48882 BC007141 BC031449 AAH31449 BE850247 BF020820 D13664 BAA02835 E05655 KM117171 AIS73059 KM117172 AIS73060 XM_006501653 XP_006501716 XM_006501654 XP_006501717 XM_006501655 XP_006501718 NM_001198765 NP_001185694 NM_001198766 NP_001185695 NM_015784 NP_056599 |
| Function | Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization. Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX. {ECO:0000269|PubMed:10404027, ECO:0000269|PubMed:20181949}. |
| Subcellular Location | Golgi apparatus. Secreted, extracellular space, extracellular matrix. Note=Colocalizes with BMP1 in the Golgi. |
| Tissue Specificity | Preferentially expressed in periosteum and periodontal ligament. Also expressed in the developing and adult heart. {ECO:0000269|PubMed:10404027, ECO:0000269|PubMed:11335131}. |
Search more
