Gene Symbol | CCT8 |
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Entrez Gene | 10694 |
Alt Symbol | C21orf112, Cctq, D21S246, PRED71 |
Species | Human |
Gene Type | protein-coding |
Description | chaperonin containing TCP1, subunit 8 (theta) |
Other Description | CCT-theta|T-complex protein 1 subunit theta|TCP-1-theta|renal carcinoma antigen NY-REN-15 |
Swissprots | B4DQH4 B4DEM7 Q4VBP8 P50990 A6NN54 |
Accessions | BAA07652 CAB90433 EAX09924 EAX09925 EAX09926 P50990 AK222490 BAD96210 AK293705 BAG57138 AK298801 BAG60936 AK308063 BC005220 BC012584 AAH12584 BC035472 BC072001 AAH72001 BC095470 AAH95470 BP248736 BU932439 D13627 BAA02792 DB301557 DC298601 Z37163 CAA85520 NM_001282907 NP_001269836 NM_001282908 NP_001269837 NM_001282909 NP_001269838 NM_006585 NP_006576 |
Function | Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin. {ECO:0000269|PubMed:20080638}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:20080638}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20080638}. |
TCP-1 θ CRISPR/Cas9 KO Plasmid (h) - sc-404844 from Santa Cruz Biotechnology
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TCP-1 θ HDR Plasmid (h) - sc-404844-HDR from Santa Cruz Biotechnology
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TCP-1 θ Double Nickase Plasmid (h) - sc-404844-NIC from Santa Cruz Biotechnology
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TCP-1 θ Double Nickase Plasmid (h2) - sc-404844-NIC-2 from Santa Cruz Biotechnology
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TCP-1 θ CRISPR Activation Plasmid (h) - sc-404844-ACT from Santa Cruz Biotechnology
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TCP-1 θ CRISPR Activation Plasmid (h2) - sc-404844-ACT-2 from Santa Cruz Biotechnology
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TCP-1 θ Lentiviral Activation Particles (h) - sc-404844-LAC from Santa Cruz Biotechnology
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TCP-1 θ Lentiviral Activation Particles (h2) - sc-404844-LAC-2 from Santa Cruz Biotechnology
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TCP-1 θ siRNA (h) - sc-43451 from Santa Cruz Biotechnology
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TCP-1 θ shRNA Plasmid (h) - sc-43451-SH from Santa Cruz Biotechnology
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TCP-1 θ shRNA (h) Lentiviral Particles - sc-43451-V from Santa Cruz Biotechnology
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CCT8 RNAi - H00010694-R01 from Novus Biologicals
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MISSION® esiRNA - EHU107891 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5674 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5674 from Sigma-Aldrich
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CCT8 siRNA (Human) - CRH7293 from Cohesion Biosciences
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CCT8 - MBS8234614 from MyBioSource
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shRNA set against Human CCT8 (NM_006585.2) - SHH258389 from Creative biogene
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shRNA set against Human CCT8(NM_006585.2) - SHG154459 from Creative biogene
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Human CCT8 siRNA - orb267795 from Biorbyt
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CCT8 shRNA Plasmid (Human) - CHH7293 from Cohesion Biosciences
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CCT8 miRNA 3'UTR clone - MiUTR1H-01837 from Creative biogene
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