| Gene Symbol |
PPP2R2A
|
| Entrez Gene |
5520
|
| Alt Symbol |
B55A, B55ALPHA, PR52A, PR55A
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
protein phosphatase 2, regulatory subunit B, alpha
|
| Other Description |
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR52), alpha isoform|serine/threonine protein phosphatase 2A, 55 KDA regulatory subunit B, alpha isoform|serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform
|
| Swissprots |
B2RBU8 P63151 B4E1T7
|
| Accessions |
EAW63577 EAW63578 EAW63579 EAW63580 P63151 AI814790 AK095153 AK123721 AK303981 BAG64899 AK314823 BAG37345 AY189686 AAO85219 BC041071 AAH41071 BX440554 CR936829 DB451813 M64929 AAA36490 XM_005273559 XP_005273616 XM_005273560 XP_005273617 XM_011544565 XP_011542867 XM_011544566 XP_011542868 XM_011544567 XP_011542869 XM_011544568 XP_011542870 XM_011544569 XP_011542871 XR_949430 NM_001177591 NP_001171062 NM_002717 NP_002708
|
| Function |
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
|
| Tissue Specificity |
Expressed in all tissues examined. {ECO:0000269|PubMed:1849734}.
|
| Top Pathways |
Dopaminergic synapse, mRNA surveillance pathway, PI3K-Akt signaling pathway, Hepatitis C, Hippo signaling pathway
|
![Western Blot: PPP2R2A Overexpression Lysate (Adult Normal) [NBL1-14694] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PPP2R2A.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2434_PPP2R2A%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-14694-img0002.jpg)